The device can chill nerves as small as a few millimeters across, but more testing and modifications are necessary before it could relieve pain in humans.

And how do scientists go about answering that question?

The University of Guelph neuroscientist is scoping out the brain regions and genes that change as a consequence of pain that lasts for months or even years.

Human data and experiments in mice challenge the common use of anti-inflammatory drugs to treat pain.

Abnormal sympathetic neuron growth leads to simultaneous activation of clusters of sensory neurons, causing the difficult-to-treat sensation.

David Julius and Ardem Patapoutian won this year’s Nobel Prize in Physiology or Medicine for their research on the ion channels involved in perceiving heat, cold, pain, and touch.

Prolonged exposure to morphine triggers cells in the spine to release signaling molecules that increase pain sensitivity and dull the relief of the drug. Blocking this activity could improve pain management.

Patients in a small trial said their chronic pain improved an average of 90 percent over the course of 15 days, but returned shortly after the electrical stimulation sessions ended.

Research in mice suggests that moderating nerve activity with drugs or electrical pulses could modify tissue immune responses, curtailing the chronic pain often associated with inflammatory conditions.

After resigning from the University of New England last year, Geoffrey Bove continues to study the effects of massage on rats in a facility he set up in his house.

The animals adopt the emotional state of their cagemates, and the parts of the brain engaged during the process are different for pain and fear, according to a new study.

Affectionate touches tap into the nervous system’s rest and digest mode, reducing the release of stress hormones, bolstering the immune system, and stimulating brainwaves linked with relaxation.

A combination of videography, machine learning, and brain imaging has identified facial expressions and neural activity patterns in mice that are associated with their emotions.

Only an equal mixture of THC and CBD has been adequately tested, and it failed to alleviate pain in cancer patients.

An experimental tissue engineering treatment that addresses damage at both the inner core and outer ring of sheep intervertebral discs improves spinal structure and function.

The findings could represent a novel mechanism for relieving inflammatory pain.