In a condition called mechanical allodynia, when everyday activities exact misery, the same neurons that ordinarily transmit normal touch are involved in feelings of pain.

Expressions of pain and orgasm are distinguishable, study finds.

Researchers silence pain neurons in the mouse spinal cord with injections of botulinum toxins modified to bind to the neurons’ receptors.

The coming legalization of recreational marijuana is already increasing funding for studies, but regulations on such research have been slow to change.

The announcement comes after an agency working group recommends against an industry partnership on ethical grounds.

Screaming obscenities when you stub your toe makes perfect biological sense.

A background in physiotherapy helps the Oxford-based researcher mix basic science with clinical work to better understand pain stemming from nerve compression.

Immune-like cells in the central nervous system are now recognized as key participants in the creation and maintenance of persistent pain.

The race to develop analgesic drugs that inhibit sodium channel Na_V1.7 is revealing a complex sensory role for the protein.