Fecal Transplant Could Boost Immunotherapy to Treat Melanoma
Fecal Transplant Could Boost Immunotherapy to Treat Melanoma
The results from two Phase 1 trials bolster the case that the gut microbiome plays a role in response to the drugs.
Fecal Transplant Could Boost Immunotherapy to Treat Melanoma
Fecal Transplant Could Boost Immunotherapy to Treat Melanoma

The results from two Phase 1 trials bolster the case that the gut microbiome plays a role in response to the drugs.

The results from two Phase 1 trials bolster the case that the gut microbiome plays a role in response to the drugs.

PD-1
Tuberculosis Can Emerge After Cancer Immunotherapy
Tuberculosis Can Emerge After Cancer Immunotherapy
Ashley Yeager | Apr 1, 2019
At least a handful of patients have developed active TB after receiving cancer treatment designed to boost the immune system’s antitumor response.
Contending with Resistance in Cancer Immunotherapy
Contending with Resistance in Cancer Immunotherapy
Marissa Fessenden | Apr 1, 2019
Researchers describe ways to study how cancer cells evade therapies that harness the immune system.
Infographic: CAR-T Cells in Solid Versus Liquid Cancers
Infographic: CAR-T Cells in Solid Versus Liquid Cancers
Kerry Grens | Apr 1, 2019
Tumor accessibility, heterogeneity, and microenvironment vary between the two classes of malignancies.
Fecal Transplant Heals Colitis Caused by Immunotherapy
Fecal Transplant Heals Colitis Caused by Immunotherapy
Anna Azvolinsky | Nov 12, 2018
A case study of two patients with advanced cancer shows it might be possible to avoid a common and severe side effect of immunotherapy treatment.
Drug Cocktail Slows Progress of Aggressive Breast Cancer
Drug Cocktail Slows Progress of Aggressive Breast Cancer
Ashley P. Taylor | Oct 22, 2018
Checkpoint inhibition combined with chemotherapy gives patients with triple-negative metastatic breast cancer about two months more time without significant tumor growth, a study finds.
James Allison and Tasuku Honjo Win Nobel Prize
James Allison and Tasuku Honjo Win Nobel Prize
Ashley Yeager, Kerry Grens | Oct 1, 2018
The immunologists, honored with the 2018 award in Physiology or Medicine, pioneered immunotherapy, which harnesses the body’s immune system to fight cancer.
Opinion: Learning from Immunotherapy’s Recent Failures
Opinion: Learning from Immunotherapy’s Recent Failures
Luis Felipe Campesato | Aug 1, 2018
The promise of immunotherapy is real. We now need to figure out how to maximize the number of patients the approach benefits.
Immune Therapy Improves Lung Cancer Patients’ Survival
Immune Therapy Improves Lung Cancer Patients’ Survival
Jim Daley | Apr 16, 2018
Pembrolizumab combined with chemotherapy nearly doubles survival rates and shrinks tumors in some individuals.
PD-L1 in Extracellular Vesicles May Help Glioblastoma Evade Immunotherapies
PD-L1 in Extracellular Vesicles May Help Glioblastoma Evade Immunotherapies
Jim Daley | Mar 8, 2018
The discovery suggests that the immune checkpoint can operate at a further distance from tumor cells than previously believed.
Immune Checkpoint Found Lacking in Type 1 Diabetes
Immune Checkpoint Found Lacking in Type 1 Diabetes
Ruth Williams | Nov 15, 2017
Boosting levels of a the immunosuppressive protein PD-L1 in blood stem cells halts diabetes in a mouse model of the disease.
Cancers Relapse by Feeding Off Immune Signals
Cancers Relapse by Feeding Off Immune Signals
Shawna Williams | Oct 16, 2017
In mice, the tumor cells are able to thwart the immune response that would kill them—but immunotherapy prevented the return of melanoma.
Gene Mutations Foretell Immunotherapy Response
Gene Mutations Foretell Immunotherapy Response
Aggie Mika | Jun 12, 2017
A drug that blocks an immune checkpoint protein effectively treats tumors in patients with deficient DNA repair genes.