Opinion: Learning from Immunotherapy’s Recent Failures
Opinion: Learning from Immunotherapy’s Recent Failures
The promise of immunotherapy is real. We now need to figure out how to maximize the number of patients the approach benefits.
Opinion: Learning from Immunotherapy’s Recent Failures
Opinion: Learning from Immunotherapy’s Recent Failures

The promise of immunotherapy is real. We now need to figure out how to maximize the number of patients the approach benefits.

The promise of immunotherapy is real. We now need to figure out how to maximize the number of patients the approach benefits.

PD-1
Immune Therapy Improves Lung Cancer Patients’ Survival
Immune Therapy Improves Lung Cancer Patients’ Survival
Jim Daley | Apr 17, 2018
Pembrolizumab combined with chemotherapy nearly doubles survival rates and shrinks tumors in some individuals.
PD-L1 in Extracellular Vesicles May Help Glioblastoma Evade Immunotherapies
PD-L1 in Extracellular Vesicles May Help Glioblastoma Evade Immunotherapies
Jim Daley | Mar 8, 2018
The discovery suggests that the immune checkpoint can operate at a further distance from tumor cells than previously believed.
Immune Checkpoint Found Lacking in Type 1 Diabetes
Immune Checkpoint Found Lacking in Type 1 Diabetes
Ruth Williams | Nov 15, 2017
Boosting levels of a the immunosuppressive protein PD-L1 in blood stem cells halts diabetes in a mouse model of the disease.
Cancers Relapse by Feeding Off Immune Signals
Cancers Relapse by Feeding Off Immune Signals
Shawna Williams | Oct 16, 2017
In mice, the tumor cells are able to thwart the immune response that would kill them—but immunotherapy prevented the return of melanoma.
Gene Mutations Foretell Immunotherapy Response
Gene Mutations Foretell Immunotherapy Response
Aggie Mika | Jun 12, 2017
A drug that blocks an immune checkpoint protein effectively treats tumors in patients with deficient DNA repair genes.