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Artist’s rendition of two X chromosomes in blue, with a glowing orange line swirling around one.
Male and Female Stem Cells Derived from One Donor in Scientific First
Studying otherwise identical XY, XX, X0, and XXY pluripotent stem cells will allow researchers to investigate sex-based differences in greater depth.
Male and Female Stem Cells Derived from One Donor in Scientific First
Male and Female Stem Cells Derived from One Donor in Scientific First

Studying otherwise identical XY, XX, X0, and XXY pluripotent stem cells will allow researchers to investigate sex-based differences in greater depth.

Studying otherwise identical XY, XX, X0, and XXY pluripotent stem cells will allow researchers to investigate sex-based differences in greater depth.

Sex chromosomes
Blue 3D illustration of X-shaped chromosomes
X Chromosome Silenced in Some Cancers in Males
Natalia Mesa, PhD | Nov 11, 2022 | 3 min read
A study finds that XIST, the gene that shuts down one X chromosome in people who have two, is linked to cancer in males. 
mixing blue and pink smoke, symbolic of the muddled boundaries between sexes
Opinion: Biological Science Rejects the Sex Binary, and That’s Good for Humanity
Agustín Fuentes | May 12, 2022 | 5 min read
Evidence from various sciences reveals that there are diverse ways of being male, female, or both. An anthropologist argues that embracing these truths will help humans flourish.
Infographic: How Some X-Chromosome Genes Escape Inactivation
Amber Dance | Mar 1, 2020 | 2 min read
About one-quarter of the hundreds of genes on the inactivated X chromosome in XX cells manage to escape that silencing, at least some of the time.
Genes that Escape Silencing on the Second X Chromosome May Drive Disease
Amber Dance | Mar 1, 2020 | 10+ min read
When X-linked genes evade silencing on the “inactive” chromosome in XX cells, some protect women from diseases such as cancer, but others seem to promote conditions such as autoimmunity.
Unbalanced Chromosomal Inheritance More Common than Thought
Jef Akst | Oct 11, 2019 | 2 min read
A genomic analysis from 23andMe suggests that people inherit two copies of a chromosome from only one parent nearly twice as often as researchers had realized.
nettie stevens x and y chromosome name origin the scientist
How Chromosomes X and Y Got Their Names, 1891
Joseph Keierleber | Mar 1, 2019 | 3 min read
A quirk of nomenclature originates in the study of insect cells.
Fruit Fly Geneticist Bruce Baker Dies
Diana Kwon | Jul 30, 2018 | 2 min read
The Stanford University professor was known for his work on sex determination and courtship in flies.
Why, Oh Y?
Jef Akst | Jan 1, 2015 | 9 min read
A toothpick and a bit of chance shaped David Page’s career, which he has dedicated to understanding the mammalian Y chromosome and fetal germ cell development.
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