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Closeup of a pair of hands in blue gloves holding a white mouse and injecting it with an amber colored liquid.
Opioids Recruit the Immune System to Cause Withdrawal Symptoms
A study finds that T cells induced by heroin cross the blood-brain barrier to wreak havoc on the brain, hinting at new ways to prevent withdrawal.
Opioids Recruit the Immune System to Cause Withdrawal Symptoms
Opioids Recruit the Immune System to Cause Withdrawal Symptoms

A study finds that T cells induced by heroin cross the blood-brain barrier to wreak havoc on the brain, hinting at new ways to prevent withdrawal.

A study finds that T cells induced by heroin cross the blood-brain barrier to wreak havoc on the brain, hinting at new ways to prevent withdrawal.

study story
three black mice lined up next to each other. the one on the left, fed a low-fat diet, has one small bald patch, the middle mouse, fed fish oil, has a large bald spot across its shoulders and back, and the right mouse, fed cocoa butter, has no baldness.
Fish Oil in Diet Can Cause Hair Loss in Mice, Study Finds
Katherine Irving | Jan 19, 2023 | 3 min read
The oil’s omega-3 fatty acids accumulate in the mice’s skin, triggering an immune response that causes hair loss.
A younger-looking mouse next to an older-looking one
Epigenetic Manipulations Can Accelerate or Reverse Aging in Mice
Alejandra Manjarrez, PhD | Jan 12, 2023 | 4 min read
Repairing damaged DNA appears to drive aging by causing the loss of epigenetic information, but restoring that information reverses such effects, a study finds.
A colored microscopy image of a dividing breast cancer cell
Transfer RNAs Have a Surprising Role in Breast Cancer Growth
Natalia Mesa, PhD | Jan 5, 2023 | 4 min read
A particular leucine-ferrying tRNA is more abundant in cancerous cells than healthy ones, and lowering its levels inhibits cancer growth, a study finds.
illustration of T cell attached to protein
“Smarter” CAR T Cells Target Tumors with Precision
Natalia Mesa, PhD | Dec 16, 2022 | 5 min read
Two studies in mice now show that researchers can control when and where CAR T cells are active, potentially overcoming previous hurdles for CAR T–based treatments.
a white mouse sits on a blue exercise wheel, looking out onto the shavings below
Mice With a Healthy Gut Microbiome Are More Motivated to Exercise
Katherine Irving | Dec 16, 2022 | 4 min read
A neural pathway between the gut and the brain led to the release of dopamine when the mice ran on a wheel or treadmill, but only in the presence of a robust microbiome. 
Artist’s rendition of the molecular structure of a ribosome (blue and purple) as it produces a polypeptide chain (red) from an mRNA template (orange and gray), with tRNA molecules (dark purple) shuttling amino acids.
Specialized Sperm Ribosomes Are Key to Male Fertility in Mice
Dan Robitzski | Dec 15, 2022 | 4 min read
A previously unknown kind of ribosome is responsible for folding sperm proteins, which decay before fertilization if prepared by other ribosomes.
Blue glowing neuron projections
Silent Synapses May Provide Plasticity in Adulthood
Holly Barker | Dec 13, 2022 | 4 min read
Inactive synapses—found on tiny neuronal projections called filopodia—are abundant in the adult brain, a mouse study suggests.
Human hand with white glove holding a white mouse in a green background.
Study Traces a Neural Circuit Behind Green Light–Mediated Pain Relief
Alejandra Manjarrez, PhD | Dec 9, 2022 | 4 min read
A mouse study concludes color-detecting cones in the eye and a subset of neurons in the brain’s thalamus are why green light exposure has an analgesic effect.
Artist’s rendition of neural connections, with inactive neurons in the background
Ketamine Flips a “Switch” in Mice’s Brain Circuitry: Study
Andy Carstens | Dec 9, 2022 | 6 min read
After injecting moderate doses of the dissociative anesthetic into the animals, previously “awake” brain cells go dark, and those that had been dormant suddenly light up.
a round water flea is illustrated in black and white on a striated background
Environmental RNA Reveals Heat Stress in Water Fleas
Katherine Irving | Dec 2, 2022 | 5 min read
The eRNA detection method could one day be used to catch early warning signs of distress in wild ecosystems. 
A brown and gray Daubenton’s bat in midair, flying in the general direction of the camera with wings outstretched and mouth open.
Duplicated Gene Helps Bats Survive “Arms Race” With Viruses
Dan Robitzski | Nov 23, 2022 | 5 min read
Bats are known for staying healthy even while harboring viral infections. Now, research sheds light on how their unusual immune system evolved.
illustration of cancer cells moving
Cancer Cells Gather Speed in Thicker Fluids
Holly Barker | Nov 22, 2022 | 4 min read
Viscous solutions accelerate the migration of tumor cells and may enable metastasis, according to a new study.
A mouse in front of an open sack of grain.
Mice Fed a Highly Processed Diet Are More Susceptible to the Flu
Alejandra Manjarrez, PhD | Nov 18, 2022 | 3 min read
It’s not clear why grain-fed mice are better able to recover after infection, but a study’s findings suggest food type may skew the results of animal studies.
A nine-banded armadillo walking on dry grass.
Leprosy Bacterium Rejuvenates Armadillos’ Livers
Alejandra Manjarrez, PhD | Nov 15, 2022 | 4 min read
Mycobacterium leprae appeared to reprogram the animals’ livers to a state partially resembling early development, resulting in healthy organ growth.
person in white jacket putting bandaid on arm of child
Can We Predict How Well Someone Will Respond to a Vaccine?
Natalia Mesa, PhD | Nov 14, 2022 | 7 min read
Researchers find signatures pre- and post-vaccination that correlate with a more robust immune response. 
a small black mouse sits next to an obese black mouse on a white background
Obesity Protects Against Genital Herpes in Mice, Study Finds
Katherine Irving | Nov 11, 2022 | 3 min read
A high-fat diet induced changes to the animals’ vaginal microbiomes that boosted survival after exposure to the virus.
Rows of soybean plants with green leaves beneath a partially clouded sky with the rising sun in the background.
As Carbon Dioxide Goes Up, Plants’ Nutrient Content Declines
Dan Robitzski | Nov 3, 2022 | 5 min read
Abundant environmental CO2 can increase plant biomass and photosynthesis, but it has downsides for agriculture and ecosystems, a growing body of research finds.
a middle-aged male scientist wearing a white lab coat points at a computer screen while a younger woman scientist also wearing a lab coat looks on.
Younger Scientists Are More Innovative, Study Finds
Katherine Irving | Oct 28, 2022 | 5 min read
On average, researchers’ impact dropped by one-half to two-thirds over their careers.
woman entering MRI machine on platform
Researchers Report Decoding Thoughts from fMRI Data
Grace van Deelen | Oct 20, 2022 | 5 min read
A method appears to be the first to noninvasively reconstruct language from brain activity.
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