A leading scientist on the mechanisms of action of antimalarial medications, the University of North Carolina professor made contributions to research and mentoring all around the world.
Plasmodium falciparum has shown an ability to evade everything we throw at it, most recently artemisinin-based combination therapies, today’s front-line treatment.
Researchers efficiently clear mice of the parasites that cause leishmaniasis, Chagas disease, and sleeping sickness by inhibiting the parasites’ kinetoplastid proteasomes.
Cases of the mosquito-borne infection are on the rise, with most reported in Brazil. The U.S. has confirmed at least two cases to date, including a recent importation into Texas.