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Technology Makes DNA Isolation, Purification Simple And Swift

WIZARD SERIES: Promega Corp. offers a variety of DNA purification products. One of the first steps that biologists perform in the quest to identify a gene, learn the function of a particular protein, or identify the perpetrator of a violent crime is to purify the genetic material away from other cellular constituents. Where once purifications were nearly as complicated as the biophysical assays performed on the products, now they are in many cases the simplest part of the experiment. While man

Written byHolly Ahern
| 9 min read

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WIZARD SERIES: Promega Corp. offers a variety of DNA purification products.
One of the first steps that biologists perform in the quest to identify a gene, learn the function of a particular protein, or identify the perpetrator of a violent crime is to purify the genetic material away from other cellular constituents. Where once purifications were nearly as complicated as the biophysical assays performed on the products, now they are in many cases the simplest part of the experiment. While many scientists continue to isolate DNA from their biological samples by methods that are tried and true, products for the simple and swift isolation of both DNA and RNA from sources as diverse as bacteria and human cells abound.

Scientists have numerous reasons for wanting to purify DNA. Molecular biologists use cloned genes to examine how regulatory proteins interact with specific regions in DNA, for example, or to create mutant ...

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    Holly Ahern is a science writer and an assistant professor of biology at Adirondack Community College in Queensbury, N.Y.

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