The Age of Senescence

Judy Campisi's work on cancer may reveal the secrets of (not) getting older

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It was hormones that drew Judith Campisi to study science: her own hormones, that is. ?I went to an all-girl Catholic high school,? she laughs, ?and I decided I?d had enough of the girls. I wanted to be where the boys were, and the boys were in the sciences.? But it was the excitement of lab life that kept her there. ?Science is always challenging, it?s never dull,? says Campisi, now a researcher at the Lawrence Berkeley Labs and the Buck Institute for Age Research.

?She?s an outstanding scientist,? says Art Pardee, Campisi?s postdoctoral advisor, of the Dana-Farber Cancer Institute and Harvard Medical School. In Pardee?s lab, Campisi examined the cell-cycle profiles of cancer cells and their normal counterparts. One experiment involved labeling cells with thymidine to track their replication and then collecting samples for several days. ?Judy was a machine,? recalls Estela Medrano of the Baylor College of Medicine ...

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