The "Eppy"

Credit: COURTESY OF EPPENDORF AG" /> Credit: COURTESY OF EPPENDORF AG Near the end of 1962, Wilhelm Bergmann, an Eppendorf development engineer, designed the first successful disposable tube for handling microliter volumes. Employing the durability of polypropylene, which can withstand centrifugation speeds up to 30,000 times that of gravity (or more depending on the fit of the centrifuge), and designed with a tight-fitting, attached lid that can be opened and closed with one han

Written byReza Hashemi
| 1 min read

Register for free to listen to this article
Listen with Speechify
0:00
1:00
Share

Near the end of 1962, Wilhelm Bergmann, an Eppendorf development engineer, designed the first successful disposable tube for handling microliter volumes. Employing the durability of polypropylene, which can withstand centrifugation speeds up to 30,000 times that of gravity (or more depending on the fit of the centrifuge), and designed with a tight-fitting, attached lid that can be opened and closed with one hand, the tube quickly became popular among clinical disciplines.

Now generally known as the Eppendorf tube, these formed the backbone of the so-called microliter system along with the piston-stroke pipette, the microliter centrifuge, and the thermomixer, and their use soon expanded into biology and biotechnology. Today, roughly three billion tubes are manufactured each year.

On the right is the blueprint for the 3810 model, the founding Eppendorf, which went from first drawing to final release in eight months (as seen through the signatures at bottom left). This model ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Meet the Author

Published In

Share
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies