Skip to main content

The Gears of the Sleep Clock

The Gears of the Sleep Clock Is replenishment of resources the key to the sleep/wake cycle? By Allan Pack Artwork by Michael Morgenstern man coming off his night shift gets into his car. He knows it's the most dangerous part of his day, a time when his body aches for sleep. He struggles to stay awake while driving home. He's tried coffee. He's tried driving with the windows open, or cranking the air conditioning up high. He's tried

Written byAllan Pack
| 8 min read

Register for free to listen to this article
Listen with Speechify
0:00
8:00

By Allan Pack

man coming off his night shift gets into his car. He knows it's the most dangerous part of his day, a time when his body aches for sleep. He struggles to stay awake while driving home. He's tried coffee. He's tried driving with the windows open, or cranking the air conditioning up high. He's tried keeping a Vicks menthol inhaler on hand. So every day he makes a pit stop at the local gas station and buys a bag of ice, and as he turns onto the highway, applies it to different parts of his anatomy to try to keep himself awake and driving safely.

This shift worker's story made an impression on me when I first heard it over 10 years ago. At the time, there was a lot of focus on circadian clocks and the molecular basis of their effect on sleep-wake cycles. Indeed, the ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member?
Add The Scientist as a preferred source on Google

Add The Scientist as a preferred Google source to see more of our trusted coverage.

Meet the Author

Published In

Related articles background image
The Scientist Digest cover September 2026
September 2026

Multiplex Microscopy Becomes Easier with Encoded Antibodies

A new system that enables researchers to uniquely tag monoclonal antibodies for use in microscopy could help simplify complex imaging studies.

View this Issue
Essential Genes Are Dominantly Activated by Single Transcription Factors

Essential Genes Are Dominantly Activated by Single Transcription Factors

EpiCypher Logo
Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Alamar Biosciences logo
Engineering CAR-Neutrophils In Vivo to Target Glioblastoma

Engineering CAR-Neutrophils In Vivo to Target Glioblastoma

Miltenyi
Best Practices for qPCR Assay Design and Optimization

Best Practices for qPCR Assay Design and Optimization

Bio-Rad

Products

Closeup image of a multi channel pipette dispensing pink liquid into a 96-well plate.

The ASSIST PLUS pipetting robot for affordable workflow automation

Integra Logo
Single cells in suspension

Rapidly isolate primary cells and make uniform single-cell suspensions with Corning® Cell Strainers

Corning logo
Abstract image representing cell membranes linked together.

CellBrite® Steady Membrane Stain: Cell surface staining built for real-time imaging

Biotium
sino biological logo

Monod Bio Licenses AI-designed Protein Technologies to SignalChem Biotech for Custom Discovery Assays