The Science of Collaboration

Time has turned one wall in Robert Weinberg's office at the Whitehead Institute for Biomedical Research into a family photo gallery. Across the room, a tangle of tropical plants has grown as thick as the record of his 20 years of collaborative research. Weinberg, a world-renowned biologist and cancer researcher, was a Massachusetts Institute of Technology professor in 1982 when David Baltimore, the Whitehead's first director, asked him to become a founding member of the fledgling institute in Ca

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A few blocks away at the Whitehead/MIT Center for Genome Research, Chad Nusbaum sits in his office. Except for the physical map of the mouse genome on one wall, the room is decorated economically. Nusbaum came to the Whitehead four years ago, drawn by the same promise of scientific freedom and collegial cross-pollination that enticed Weinberg almost 20 years earlier. "I was really impressed and really excited," says Nusbaum, the center's co-director of sequencing and analysis. "I was immediately impressed by the quality of the operation. It was so far ahead of anything I had been involved with."

By most measures, the Whitehead Institute and its impressive array of internationally renowned scientists is still regarded among the world's finest biomedical research centers. But on the eve of its 20th anniversary, any story about the Whitehead Institute is really a tale of two research centers. The established laboratories of its founding ...

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