Time to Abandon the Three Rs

Submitting to ?refinement, reduction, and replacement? risks the future of animal research

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The best hopes to treat or cure any number of diseases all rely on current animal experiments. Like all science, the investigations that scientists perform with animals increase our knowledge of nature and can therefore increase the possibilities for human action, advancing the cause of human freedom. So why do scientists persist in denigrating their own behavior by advocating the three Rs: refinement, reduction, and replacement?

In the United Kingdom, since the passage of the 1986 Animals (Scientific Procedures) Act, researchers must obtain a license from the Home Office, which involves an assessment of the invasiveness of the study and the species used, following the principles of the three Rs. Invariably, licensing will require considerable justification for any procedures that involve distressing the animal, and considerable pressure will be applied for the use of fewer animals, and from further down the phylogenetic tree (such as using rats rather than primates). ...

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  • Stuart W.G. Derbyshire

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