Top 7 papers in cell biology

Just in time for ASCB -- see the cell biology articles most highly ranked by F1000

Written byJef Akst
| 3 min read

Register for free to listen to this article
Listen with Speechify
0:00
3:00
Share
linkurl:1. Immune response feeds parasite;http://f1000.com/5337958?key=jy9by8r71p0ctb7
Color-enhanced scanning electron micrograph showing Salmonella typhimurium (red) invading cultured human cells.
Image: Wikimedia commons, NIAID, NIH
Salmonella is able to outcompete resident gut microbes by deriving energy from the inflammatory immune response that is supposed to combat the pathogen. S.E. Winter, et al., "Gut inflammation provides a respiratory electron acceptor for Salmonella," linkurl:Nature,;http://www.ncbi.nlm.nih.gov/sites/entrez/20864996?dopt=Abstract&holding=f1000%2Cf1000m 467:426-9, 2010. Evaluated by Matam Vijay-Kumar and Andrew Gewirtz, Emory University; David Alpers, Washington University School of Medicine; Alexei Kurakin and Roya Khosravi-Far, Beth Israel Deaconess Medical Center; Michael Hensel, University of Osnabrück; Yvonne Sun and Mary O'Riordan, University of Michigan Medical School; Wolf-Dietrich Hardt, Swiss Federal Institute of Technology; James Moir, University of York; Victor Nizet, University of California, San Diego. linkurl:Free F1000 evaluation;http://f1000.com/5337958?key=jy9by8r71p0ctb7 linkurl:2. Piezos for pain;http://f1000.com/5074956?key=508sw6dkxkj0bc5 A family of proteins, called Piezos, may be components of mechanically activated ion channels which make possible several senses, such as hearing, touch and pain sensation. B. Coste, et al., "Piezo1 and Piezo2 are essential components of distinct mechanically activated cation channels," linkurl:Science,;http://www.ncbi.nlm.nih.gov/sites/entrez/20813920?dopt=Abstract&holding=f1000%2Cf1000m 330:55-60, 2010. Evaluated by M. Moran & D. Kimball, Hydra Biosciences; J. Garcia-Anoveros, Northwestern University; F. Viana, UMH Instituto de Neurociencias; P. Garrity, Brandeis Univ; B. Nilius, KU Leuven. linkurl:Free F1000 evaluation;http://f1000.com/5074956?key=508sw6dkxkj0bc5 linkurl:3. New function for noncoding RNAs;http://f1000.com/5601958?key=pvf5hhgm9nltp41 Long noncoding RNAs, previously known to silence expression of certain genes, also play a role in gene activation. U.A. Ørom, et al., "Long noncoding RNAs with enhancer-like function in human cells," linkurl:Cell,;http://www.ncbi.nlm.nih.gov/sites/entrez/20887892?dopt=Abstract&holding=f1000%2Cf1000m 143(1):46-58, 2010. Evaluated by L. Ringrose, Inst of Molecular Biotechnology GmbH; A. Clery, Dominik Theler & F. Allain, ETH; J. Abrams, U of Texas Southwestern Med Cen at Dallas; H. Steinbeisser, Univ of Heidelberg; E. Lara-Pezzi & N. Rosenthal, EMBL. linkurl:Free F1000 evaluation;http://f1000.com/5601958?key=pvf5hhgm9nltp41 linkurl:4. Proficient pluripotency;http://f1000.com/5684958?key=0bblfdljr3hfgg8 Researchers created synthetic mRNAs that boost the efficiency of human cell reprogramming, marking a significant advance in induced pluripotent stem (iPS) cell technology. L. Warren, et al., "Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA," linkurl:Cell Stem Cell,;http://www.ncbi.nlm.nih.gov/sites/entrez/20888316?dopt=Abstract&holding=f1000%2Cf1000m 7(5):618-30, 2010. Evaluated by R. Juliano, Univ North Carolina; B. Aranda-Orgilles & I. Aifantis, HHMI/NYU School of Med; K. Maass & G. Fishman, NYU Langone Med Cen; A. Kriegstein, UCSF. linkurl:Free F1000 evaluation;http://f1000.com/5684958?key=0bblfdljr3hfgg8 linkurl:5. Details of cell division;http://f1000.com/4884975?key=377m7xt67t8w91tA complex of proteins crucial for the alignment and separation of chromosomes in dividing cells is directed to the centromeres by the phosphorylating actions of a specific kinase, revealing an important mechanism of cell division that has long escaped scientists. F. Wang, et al., "Histone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis," linkurl:Science,;http://www.ncbi.nlm.nih.gov/sites/entrez/20705812?dopt=Abstract&holding=f1000%2Cf1000m 2010 Aug 12 doi: 10.1126/science.1189435. Evaluated by W. Earnshaw, Univ of Edinburgh; E. Avvedimento, Univ Federico II; S. Ems-McClung & C. Walczak, Indiana Univ; R. Medema, Univ. Med Cen Utrecht, Netherlands; K. Lee, NIH. linkurl:Free F1000 evaluation;http://f1000.com/4884975?key=377m7xt67t8w91t linkurl:6. Color processing connections;http://f1000.com/5691956?key=ysrqdqp5xdtjy7pMulti-electrode recordings of macaque retinal ganglia allow scientists to map the neural pathways underlying color vision at single-cone resolution, providing insights regarding the functional connectivity of the retinal circuit. G.D. Field, et al., "Functional connectivity in the retina at the resolution of photoreceptors," linkurl:Nature,;http://www.ncbi.nlm.nih.gov/sites/entrez/20930838?dopt=Abstract&holding=f1000%2Cf1000m 467:673-7, 2010. Evaluated by Richard Born, Harvard Medical School; Bruce Cumming, NEI; Christina Joselevitch and David Zenisek, Yale University School of Medicine; David P Wolfer, University of Zurich. linkurl:Free F1000 evaluation;http://f1000.com/5691956?key=ysrqdqp5xdtjy7p linkurl:7. Better nuclei isolation;http://f1000.com/3612956?key=2pf92jhlzvl1rhh Researchers streamlined a method for tagging nuclei from specific cell types in plants, and purifying them to measure gene expression and chromatin-modification across a variety of tissue types. R.B. Deal and S. Henikoff, "A simple method for gene expression and chromatin profiling of individual cell types within a tissue," linkurl:Dev Cell,;http://www.ncbi.nlm.nih.gov/sites/entrez/20627084?dopt=Abstract&holding=f1000%2Cf1000m 18:1030-40, 2010. Evaluated by E.S. Dennis, CSIRO; E. Lam, Rutgers Univ; D. Chamovitz, Tel Aviv Univ; K. Schneitz, Technische Univ Munchen; P. Kaufman, U Mass Med School. linkurl:Free F1000 evaluation;http://f1000.com/3612956?key=2pf92jhlzvl1rhh The F1000 Top 7 is a snapshot of the highest ranked articles from a 30-day period on Faculty of 1000 Cell Biology, as calculated on December 3, 2010. Faculty Members evaluate and rate the most important papers in their field. To see the latest rankings, search the database, and read daily evaluations, visit linkurl:http://f1000.com.;http://f1000.com
**__Related stories:__***linkurl:Top 7 immunology papers;http://www.the-scientist.com/news/display/57819/
[23rd November 2010]*linkurl:Top 7 papers in medicine;http://www.the-scientist.com/news/display/57810/
[16th November 2010]*linkurl:Top 7 genetics papers;http://www.the-scientist.com/news/display/57794/
[2nd November 2010]
Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Meet the Author

  • Jef (an unusual nickname for Jennifer) got her master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses. After four years of diving off the Gulf Coast of Tampa and performing behavioral experiments at the Tennessee Aquarium in Chattanooga, she left research to pursue a career in science writing. As The Scientist's managing editor, Jef edited features and oversaw the production of the TS Digest and quarterly print magazine. In 2022, her feature on uterus transplantation earned first place in the trade category of the Awards for Excellence in Health Care Journalism. She is a member of the National Association of Science Writers.

    View Full Profile
Share
Image of small blue creatures called Nergals. Some have hearts above their heads, which signify friendship. There is one Nergal who is sneezing and losing health, which is denoted by minus one signs floating around it.
June 2025, Issue 1

Nergal Networks: Where Friendship Meets Infection

A citizen science game explores how social choices and networks can influence how an illness moves through a population.

View this Issue
An illustration of green lentiviral particles.

Maximizing Lentivirus Recovery

cytiva logo
Unraveling Complex Biology with Advanced Multiomics Technology

Unraveling Complex Biology with Five-Dimensional Multiomics

Element Bioscience Logo
Resurrecting Plant Defense Mechanisms to Avoid Crop Pathogens

Resurrecting Plant Defense Mechanisms to Avoid Crop Pathogens

Twist Bio 
The Scientist Placeholder Image

Seeing and Sorting with Confidence

BD

Products

The Scientist Placeholder Image

Waters Enhances Alliance iS HPLC System Software, Setting a New Standard for End-to-End Traceability and Data Integrity 

The Scientist Placeholder Image

Agilent Unveils the Next Generation in LC-Mass Detection: The InfinityLab Pro iQ Series

agilent-logo

Agilent Announces the Enhanced 8850 Gas Chromatograph

parse-biosciences-logo

Pioneering Cancer Plasticity Atlas will help Predict Response to Cancer Therapies