Scientists commonly create and archive samples as formaldehyde-fixed and paraffin-embedded (FFPE) tissue blocks. These blocks carry enormous preservation potential for future transcriptomic studies, but fixing and embedding tissues can cause RNA degradation, hindering reverse transcription-based transcriptome profiling. Researchers can overcome this challenge by pairing in situ hybridization with the right tissue processing and expression assay workflow.
Download this poster from 10x Genomics to discover how the new Chromium Single Cell Fixed RNA Profiling assay captures whole transcriptome expression in FFPE samples, allowing researchers to detect low-expressing genes with high sensitivity.
