What is Strip-EZTM? This new technology is incorporated into Ambion's StripAble¦ RNA Probe Synthesis Kits to optimize analysis of RNA and DNA populations using Northerns, Southerns, and related nucleic acid blots. Strip-EZ Technology (patent pending) employs modified nucleic acids that can be degraded by a reagent that does not affect standard RNA or DNA.

Standard RNA Probe
High sensitivity, Difficult to strip
RNA Probe

High Sensitivity, Easy to strip
controlStripped 2x with boiling SDScontrolStripped 1x with Strip-EZ Probe Degradation Buffer
Comparison of RNA probes and Ambion Strip-EZTM probes: Four identical Northern blots were generated using a dilution series (3, 1, 0.3, and 0.1 micrograms) of mouse lung RNA. The blots were paired and each pair was probed with 5 x 106 cpm of RNA or Strip-EZ RNA probes specific to the mouse ß-actin mRNA using Ambion's NorthernMaxTM Kit. (RNA and...

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