World’s First Chimeric Monkeys

Researchers have bred monkeys derived from six different monkey parents.

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Two rhesus monkeys made from a combination of embryonic cells from six different monkey embryos OREGON HEALTH AND SCIENCE UNIVERSITY

Researchers at the Oregon National Primate Research Center have generated the world’s first ever chimeric primates—three young monkeys derived from six distinct genomes, according to a paper published today (January 5) in Cell.

The infants—a set of twins and a singleton—were generated from 4-day-old embryos of six different rhesus monkeys stuck together early in development, then implanted into five adult females. Tests on the fetuses showed that all of the infants’ organs and tissues contained a mixture of cells carrying the different genomes, and all three monkeys that made it term appear to be healthy with no birth defects.

Although the embryos grow together into one larger embryo, "the cells never fuse," Shoukhrat Mitalipov, an associate scientist at the Oregon National Primate Research Center who ...

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Meet the Author

  • Jef Akst

    Jef Akst was managing editor of The Scientist, where she started as an intern in 2009 after receiving a master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses.
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