A new workflow for single cell sequencing, which reduces the cost of sample preparation by 90%.

Collaboration Accelerates Single Cell Genomics Research.

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TTP Labtech Ltd, a global leader in the design and development of automated instrumentation and consumables for life science applications, and the University of California San Diego (UC San Diego), have announced that their collaboration has resulted in a new workflow for single cell sequencing, which reduces the cost of sample preparation by 90%. The workflow, which has been published in the Journal of Laboratory Automation, was developed through the combination of UC San Diego’s expertise in genomics and the use of TTP Labtech’s mosquito liquid handlers, which can pipette nanolitre to microlitre volumes with high accuracy and reproducibility, to miniaturise and automate the process.

Although single-cell genomics is advancing rapidly, researchers face challenges linked with reproducibility, sensitivity, scalability and cost, particularly when trying to miniaturise high-throughput applications. To maximise accuracy and precision, library prep protocols recommend volumes that are within the range of manual pipettes or large-volume liquid handlers. ...

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