Article updated on May 9th, 2023.
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The immune system is a workhorse when it comes to protecting the body from foreign objects, including pathogenic microbes.1 Part of this protection is attributed to B cells, which produce billions of single species antibodies with unique antigen binding sites (ABSs).2 When an endogenous or exogenous antigen binds to an ABS, a series of events cause the foreign entity that the antigen is part of to be neutralized or destroyed.1 This brush-up summary reviews how researchers have adapted features of traditional antibodies to produce antibody therapeutics for disease treatments.
Antibody therapeutics are a type of biological treatment that uses antibodies to target and neutralize or attack specific antigens while minimizing damage to healthy tissues. During neutralization, antibodies bind to their target, interfering with specific signaling pathways or blocking pathogens’ interactions with host ...
