Updated
Biogen’s Alzheimer’s Drug Gets FDA Approval, Mixed Reviews
Biogen’s Alzheimer’s Drug Gets FDA Approval, Mixed Reviews
A lackluster performance in clinical trials of the monoclonal antibody aducanumab has left some experts unconvinced of its benefit.
Biogen’s Alzheimer’s Drug Gets FDA Approval, Mixed Reviews
Biogen’s Alzheimer’s Drug Gets FDA Approval, Mixed Reviews

A lackluster performance in clinical trials of the monoclonal antibody aducanumab has left some experts unconvinced of its benefit.

A lackluster performance in clinical trials of the monoclonal antibody aducanumab has left some experts unconvinced of its benefit.

monoclonal antibodies
Identifying Antibodies that Target Membrane Proteins in Their Native Conformations
Identifying Antibodies that Target Membrane Proteins in Their Native Conformations
The Scientist Creative Services Team in collaboration with OXGENE | May 10, 2021
A new mammalian display platform enhances antibody discovery for challenging protein targets.
Brain’s Lymphatic System Tied to Alzheimer’s Symptoms in Mice
Brain’s Lymphatic System Tied to Alzheimer’s Symptoms in Mice
Amanda Heidt | May 4, 2021
A dysfunctional lymphatic system, described as a clogging of the brain’s sink, may explain why immunotherapies fail in some Alzheimer’s patients.
Technique Talk: Analyzing Molecular Interactions During Monoclonal Antibody Development
Technique Talk: Analyzing Molecular Interactions During Monoclonal Antibody Development
The Scientist Creative Services Team in collaboration with Sartorius Corporation | Mar 9, 2021
In this workshop, you will learn how to measure protein interactions using Octet bio-layer interferometry.
Regeneron Cocktail Stumbles Against SARS-CoV-2 Variant in Vitro
Regeneron Cocktail Stumbles Against SARS-CoV-2 Variant in Vitro
Marcus A. Banks | Mar 1, 2021
A treatment of two monoclonal antibodies against SARS-CoV-2 is ninefold less effective in the lab against the B.1.351 variant than against the dominant version of the virus.
A Greener Recombinant Monoclonal Antibody
A Greener Recombinant Monoclonal Antibody
The Scientist Creative Services Team | Dec 9, 2020
Learn more about environmentally-friendly antibodies that deliver superior performance.
Eli Lilly Halts Antibody Trial in Hospitalized COVID-19 Patients
Eli Lilly Halts Antibody Trial in Hospitalized COVID-19 Patients
Ashley Yeager | Oct 27, 2020
Recent data show that the drug bamlanivimab, also known as LY-CoV555, does not appear to help those with severe cases of COVID-19, but trials continue for milder cases.
Antibody-Based Drug May Reduce COVID-19 Hospitalizations: Study
Antibody-Based Drug May Reduce COVID-19 Hospitalizations: Study
Lisa Winter | Sep 17, 2020
Eli Lilly reports a 72 percent reduction in hospitalization risk among patients who received its monoclonal antibody compared to those who received a placebo.
Bacterial Superglue Enables Antiviral Antibody Discovery
Bacterial Superglue Enables Antiviral Antibody Discovery
Ruth Williams | Jul 13, 2020
Testing out combinations of antiviral proteins from llamas could help researchers create potent virus-neutralizing multimers.
Putting the Brakes on SARS-CoV-2: Neutralizing Antibodies
Putting the Brakes on SARS-CoV-2: Neutralizing Antibodies
The Scientist Creative Services Team | Jul 6, 2020
Experts will discuss potential neutralizing antibodies currently under investigation for SARS-CoV-2 treatment.
First Antibody Trial Launched in COVID-19 Patients
First Antibody Trial Launched in COVID-19 Patients
Katarina Zimmer | Jun 2, 2020
In record time, scientists have gone from harvesting antibodies against SARS-CoV-2 from survivors of coronavirus infections to testing the antibodies’ safety as a drug in humans.
Scientists Scan for Weaknesses in the SARS-CoV-2 Spike Protein
Scientists Scan for Weaknesses in the SARS-CoV-2 Spike Protein
Chris Baraniuk | Apr 9, 2020
The virus’s tool for prying open host cells is coated in a protective armor of sugar—but gaps may offer vulnerability to disruption by antibodies.
UCB Cuts $2.1 Billion Deal to Acquire Ra Pharma
UCB Cuts $2.1 Billion Deal to Acquire Ra Pharma
Catherine Offord | Oct 14, 2019
The move will allow the Belgium-headquartered biopharmaceutical giant to boost its work on treatments for rare diseases.
Two Experimental Drugs Effective at Treating Ebola
Two Experimental Drugs Effective at Treating Ebola
Catherine Offord | Aug 13, 2019
REGN-EB3 and mAb114 reduced mortality in a clinical trial carried out during the ongoing outbreak in Democratic Republic of Congo.
MIT Researcher Allegedly Copied Other Groups’ Drug Designs
MIT Researcher Allegedly Copied Other Groups’ Drug Designs
Catherine Offord | May 29, 2019
Executives at a biotech that develops new antibodies argue that Ram Sasisekharan didn’t come up with the structures for at least two experimental therapies that his group has described.
John Mendelsohn, Former MD Anderson Cancer Center President, Dies
John Mendelsohn, Former MD Anderson Cancer Center President, Dies
Ashley Yeager | Jan 10, 2019
The scientist and clinician helped develop a new form of cancer therapy, using a monoclonal antibody to treat head, neck, colorectal, and lung cancers.
Ebola Clinical Trial to Begin Amid Outbreak in DRC
Ebola Clinical Trial to Begin Amid Outbreak in DRC
Ashley P. Taylor | Nov 12, 2018
The study will examine the efficacy of four drugs—an antiviral and three monoclonal antibodies—that are already being used to treat patients in Democratic Republic of Congo.
Antibody Combo Knocks Down HIV in Clinical Trials
Antibody Combo Knocks Down HIV in Clinical Trials
Kerry Grens | Sep 26, 2018
Some patients could suppress the virus without antiretroviral therapy for months after the drug infusions.
Ebola Update: More Experimental Treatments, Health Workers at Risk
Ebola Update: More Experimental Treatments, Health Workers at Risk
Catherine Offord | Aug 23, 2018
The number of cases in Democratic Republic of Congo’s latest outbreak of the virus has now surpassed 100.  
Q&A: Anthony Fauci Describes an Experimental Ebola Treatment
Q&A: Anthony Fauci Describes an Experimental Ebola Treatment
Shawna Williams | Aug 14, 2018
The monoclonal antibody, known as mAb114, is likely to be used in the current Ebola outbreak in DRC.