Cancer-Specific Antigens Encoded in “Junk” DNA
Carolyn Wilke | Apr 1, 2019
Researchers found that allegedly noncoding genetic material carries the instructions for many peptides that may help harness the immune system to fight cancer.
Novel Type of Immune Cell Discovered in Type 1 Diabetes Patients
Novel Type of Immune Cell Discovered in Type 1 Diabetes Patients
A rogue hybrid lymphocyte, bearing characteristics of both B and T cells, may play a role in driving autoimmunity in the disease, although the mechanism is far from clear.
A rogue hybrid lymphocyte, bearing characteristics of both B and T cells, may play a role in driving autoimmunity in the disease, although the mechanism is far from clear.
Researchers Build a Cancer Immunotherapy Without Immune Cells
Abby Olena | Nov 13, 2017
A team has engineered two stem cell lines into “synthetic T cells” that destroy breast cancer cells in vitro.
Compound Found in Red Wine Boosts Immune Cell Function
Catherine Offord | Oct 16, 2017
At low doses, resveratrol enhanced human T-cell activity in vitro, while at high doses it interfered with cell signaling.
DNA-Delivered Antibodies Fight Off Lethal Bacterial Infection
Catherine Offord | Oct 3, 2017
Mice receiving the treatment produced their own monoclonal antibodies and survived infection with the life-threatening pathogen Pseudomonas aeruginosa.
Image of the Day: Lights, Camera, T Cells!
The Scientist Staff | May 30, 2017
The fluid motions of a T cell’s microvilli, scanning their environment for antigens, are captured in 3-D and in real time.
Infographic: Targeting Cancer Antigens
Stephen P. Schoenberger and Ezra Cohen | Mar 31, 2017
Neoantigens may serve as valuable targets for new immunotherapies.
Enhancing Vaccine Development
Wudan Yan | Jun 1, 2016
Using proteomics methods to inform antigen selection