A tumor surrounded by an artistic conception of the tumor microenvironment.
| 3 min read
Functional antibodies are key experimental tools for targeting the complex tumor microenvironment and developing new immunotherapies.

cancer immunotherapy

Illustration showing focus on one orange-colored cell with some blue cells. Representative of cancer immunotherapy.

Tumor Cell “Pockets” May Signal Immunotherapy Success

A healthcare professional touches the arm of a seated patient who is undergoing cancer treatment.

The Cancer Immunotherapy Revolution: From Artificial Sweeteners to T-Cell Monitoring

Light yellow packets of Splenda, a common trade name for sucralose and the artificial sweetener recently found to worsen response to cancer immunotherapy, are strewn all over a white surface.

A Common Artificial Sweetener Could Disrupt Cancer Immunotherapy Response 

Conceptual image of 3D CAR T-cells depicted in blue and yellow.

Transforming CAR T-Cell Therapy Development

Sino
3D illustration of a lymphocyte binding to proteins.

BATMAN Signals T Cell Receptor Crossreactivity

A pink circle with a red dot in the center made of clay, representing an egg. Several sperm-shaped figures are swimming toward the egg from the left side. The background is a uniform light blue.

Cancer Survivors Increasingly Face Fertility Issues—What Can Be Done to Help?

A scientist uses a pipette to drop a solution onto a petri dish.

Biologics Offer a Vast Toolbox for Disease Treatment

Conceptual image of 3D multicolored antibody proteins on a black background.

Precision Meets Power: The Science Behind Bispecific Antibodies

bioxcell
Several white T cells attack a large red and yellow cancer cell.

The Innate Immune System’s Secret Weapon

Trending

A close-up image of a fly landing on a dessert

What Happens When a Fly Lands on Your Food? 

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

Image of an infant’s feet that are visible in a hospital incubator.

Record-Breaking DNA Sequencing Technology Could Transform Newborn Care

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Impersonation Scandals Shake Academic Publishing

Multimedia

Olga Anczukow and Ryan Englander discuss how transcriptome splicing affects immune system function in lung cancer.

Long-Read RNA Sequencing Reveals a Regulatory Role for Splicing in Immunotherapy Responses

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Research Roundtable: The Evolving World of Spatial Biology

Research Roundtable: The Evolving World of Spatial Biology

Image of a woman with her hands across her stomach. She has a look of discomfort on her face. There is a blown up image of her stomach next to her and it has colorful butterflies and gut bacteria all swarming within the gut.
November 2025, Issue 1

Why Do We Feel Butterflies in the Stomach?

These fluttering sensations are the brain’s reaction to certain emotions, which can be amplified or soothed by the gut’s own “bugs".

View this Issue
Olga Anczukow and Ryan Englander discuss how transcriptome splicing affects immune system function in lung cancer.

Long-Read RNA Sequencing Reveals a Regulatory Role for Splicing in Immunotherapy Responses

Pacific Biosciences logo
Research Roundtable: The Evolving World of Spatial Biology

Research Roundtable: The Evolving World of Spatial Biology

Conceptual cartoon image of gene editing technology

Exploring the State of the Art in Gene Editing Techniques

Bio-Rad
Conceptual image of a doctor holding a brain puzzle, representing Alzheimer's disease diagnosis.

Simplifying Early Alzheimer’s Disease Diagnosis with Blood Testing

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LabVantage Solutions Awarded $22.3 Million U.S Customs and Border Protection Contract to Deliver Next-Generation Forensic LIMS

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Evosep Unveils Open Innovation Initiative to Expand Standardization in Proteomics

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OGT expands MRD detection capabilities with new SureSeq Myeloid MRD Plus NGS Panel