Myeloid Cells in Cancer and Science Advocacy: A Conversation with Dr. Miriam Merad

Join us to learn about adoptive cell therapies from leading experts in the field of cancer immunology. 

Meet some of the people featured in the July/August 2020 issue of The Scientist.

Better understanding the CD8+ T cells already present in tumors could be key to making immunotherapies work for more patients.

There’s a new cell-based cancer immunotherapy on the block.

Injecting the seasonal flu vaccine directly into clumps of malignant cells recruits immune cells to confront the cancer.

This previously unknown mechanism for spotting foreign genetic material in the cytoplasm launches antiviral defenses even when the well-known immune mediator STING is absent.

The Oxford researcher’s work on lipid and peptide antigens revealed key mechanisms in inflammation, immunotherapy, and vaccination, which are being pursued in clinical trial treatments.

Research in mice and humans is beginning to establish a link between the composition of microbes in the gut and immune responses to tumor cells, but the mechanisms are not yet clear.