Ancient Giant Virus Discovered

A new species of giant virus discovered in the Siberian permafrost, where it’s been buried for 30,000 years, is reincarnated in the lab.

| 2 min read

Register for free to listen to this article
Listen with Speechify
0:00
2:00
Share

Electron microscopic image of a mimivirus, the first type of giant virus discoveredWIKIMEDIA, E. GHIGO ET AL.Discoveries of viruses with physical and genomic dimensions that challenge the very definition of these infectious agents—the so-called giant viruses—have made headlines for more than a decade now. And they’ve made the news once again this week (March 3), with the publication in PNAS of a new species that a team led by researchers at Aix-Marseille University in France discovered buried in the permafrost of Siberia.

The new virus, dubbed Pithovirus sibericum, measures 1.5 μm in length and 0.5 μm in diameter—even bigger than former record holders, the pandoraviruses, which are only 1 μm long and 0.5 μm in diameter. P. sibericum was identified as part of a survey of the virome of Siberian permafrost, isolated from a sample that’s more than 30,000 years old, according to the researchers. Nevertheless, when given access to an amoeba host in the lab, P. sibericum infected the cell, raising concerns about the possible risk such giant viruses might pose if they are released from the thawing Arctic ground.

“The revival of such an ancestral amoeba-infecting virus . . . suggests that the thawing of permafrost either from global warming or industrial exploitation of circumpolar ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Keywords

Meet the Author

  • Jef Akst

    Jef Akst was managing editor of The Scientist, where she started as an intern in 2009 after receiving a master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses.
Share
3D illustration of a gold lipid nanoparticle with pink nucleic acid inside of it. Purple and teal spikes stick out from the lipid bilayer representing polyethylene glycol.
February 2025, Issue 1

A Nanoparticle Delivery System for Gene Therapy

A reimagined lipid vehicle for nucleic acids could overcome the limitations of current vectors.

View this Issue
Enhancing Therapeutic Antibody Discovery with Cross-Platform Workflows

Enhancing Therapeutic Antibody Discovery with Cross-Platform Workflows

sartorius logo
Considerations for Cell-Based Assays in Immuno-Oncology Research

Considerations for Cell-Based Assays in Immuno-Oncology Research

Lonza
An illustration of animal and tree silhouettes.

From Water Bears to Grizzly Bears: Unusual Animal Models

Taconic Biosciences
Sex Differences in Neurological Research

Sex Differences in Neurological Research

bit.bio logo

Products

Photo of a researcher overseeing large scale production processes in a laboratory.

Scaling Lentiviral Vector Manufacturing for Optimal Productivity

Thermo Fisher Logo
Collage-style urban graphic of wastewater surveillance and treatment

Putting Pathogens to the Test with Wastewater Surveillance

An illustration of an mRNA molecule in front of a multicolored background.

Generating High-Quality mRNA for In Vivo Delivery with lipid nanoparticles

Thermo Fisher Logo
Tecan Logo

Tecan introduces Veya: bringing digital, scalable automation to labs worldwide