Ancient Giant Virus Discovered

A new species of giant virus discovered in the Siberian permafrost, where it’s been buried for 30,000 years, is reincarnated in the lab.

Written byJef Akst
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Electron microscopic image of a mimivirus, the first type of giant virus discoveredWIKIMEDIA, E. GHIGO ET AL.Discoveries of viruses with physical and genomic dimensions that challenge the very definition of these infectious agents—the so-called giant viruses—have made headlines for more than a decade now. And they’ve made the news once again this week (March 3), with the publication in PNAS of a new species that a team led by researchers at Aix-Marseille University in France discovered buried in the permafrost of Siberia.

The new virus, dubbed Pithovirus sibericum, measures 1.5 μm in length and 0.5 μm in diameter—even bigger than former record holders, the pandoraviruses, which are only 1 μm long and 0.5 μm in diameter. P. sibericum was identified as part of a survey of the virome of Siberian permafrost, isolated from a sample that’s more than 30,000 years old, according to the researchers. Nevertheless, when given access to an amoeba host in the lab, P. sibericum infected the cell, raising concerns about the possible risk such giant viruses might pose if they are released from the thawing Arctic ground.

“The revival of such an ancestral amoeba-infecting virus . . . suggests that the thawing of permafrost either from global warming or industrial exploitation of circumpolar ...

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  • Jef (an unusual nickname for Jennifer) got her master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses. After four years of diving off the Gulf Coast of Tampa and performing behavioral experiments at the Tennessee Aquarium in Chattanooga, she left research to pursue a career in science writing. As The Scientist's managing editor, Jef edited features and oversaw the production of the TS Digest and quarterly print magazine. In 2022, her feature on uterus transplantation earned first place in the trade category of the Awards for Excellence in Health Care Journalism. She is a member of the National Association of Science Writers.

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