Anti-Malarial Mosquitoes?

Artificially induced bacterial infections in mosquitoes could reduce the spread of malaria-causing parasites.

Written byRuth Williams
| 3 min read

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Anopheles stephensiWIKIMEDIA, RSABBATINICreating a stable, heritable infection of Wolbachia bacteria in Anopheles stephensi mosquitoes diminishes the insects’ chances of transmitting the human malaria-causing parasite, according to a report published today (May 9) in Science. The results suggest that such modified mosquitoes could contribute to malaria prevention strategies in the future.

“It’s a very nice demonstration that Anopheles genus, the most important disease vector mosquitoes, which haven’t previously been shown to naturally support Wolbachia infections, can indeed do so in a stable inherited manner,” said Steven Sinkins, head of the Mosquitoes & Wolbachia group in the Experimental Medicine division at the University of Oxford, UK, who was not involved in the research. “It’s all very exciting stuff in terms of developing new malaria control strategies.”

Wolbachia are parasites or endosymbionts to many insect species, even some mosquitoes, and in certain cases can protect their hosts from infection by other parasites. This protective feature led researchers to wonder whether Wolbachia might be used to prevent the spread of dangerous human parasites in their insect hosts.

Indeed, it ...

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  • ruth williams

    Ruth is a freelance journalist. Before freelancing, Ruth was a news editor for the Journal of Cell Biology in New York and an assistant editor for Nature Reviews Neuroscience in London. Prior to that, she was a bona fide pipette-wielding, test tube–shaking, lab coat–shirking research scientist. She has a PhD in genetics from King’s College London, and was a postdoc in stem cell biology at Imperial College London. Today she lives and writes in Connecticut.

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