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a newly hatched mosquito sits on top of water, with its discarded cocoon floating below
In Vitro Malaria Sporozoite Production May Lead to Cheaper Vaccines
A method for culturing the infectious stage of the Plasmodium lifecycle could increase malaria vaccine production efficiency by tenfold, study authors say.
In Vitro Malaria Sporozoite Production May Lead to Cheaper Vaccines
In Vitro Malaria Sporozoite Production May Lead to Cheaper Vaccines

A method for culturing the infectious stage of the Plasmodium lifecycle could increase malaria vaccine production efficiency by tenfold, study authors say.

A method for culturing the infectious stage of the Plasmodium lifecycle could increase malaria vaccine production efficiency by tenfold, study authors say.

malaria
Three flying foxes (a type of bat) hanging upside down on a bare branch
Climate Change, Deforestation Drive Bat Virus Spillover Into Humans
Amanda Heidt | Nov 17, 2022 | 4 min read
Bats that experience food shortages due to climate change and habitat loss end up roosting in urban settings, where they shed more of the deadly Hendra virus. 
An orange toad perched on a leaf
Past Malaria Surges Linked to Amphibian Die-off
Andy Carstens | Sep 21, 2022 | 2 min read
A study suggests that pathogens affecting other species can indirectly harm human health.
Mosquito on leaf stock photo
Combating Mosquito-Borne Diseases with CRISPR
Niki Spahich, PhD | 4 min read
As alternatives to insecticides, Omar Akbari uses sophisticated genetic engineering methods to solve the world’s mosquito problems.
Pink and purple <em>Plasmodium</em> parasites inside red blood cells
Malarial Host-Parasite Clash Causes Deadly Blood Sugar Drop
Natalia Mesa, PhD | Jul 18, 2022 | 4 min read
Scientists say they have finally figured out why some people with severe malaria end up with dangerous hypoglycemia, also reporting that the condition starves the parasite into changing tactics from virulence to transmission.
A mosquito sucks blood from human skin
Malaria Mosquitoes Bite More During the Day Than Previously Thought
Andy Carstens | May 17, 2022 | 2 min read
While malaria control strategies have focused on mosquitoes’ nocturnal activity, almost one-third of bites occur while the sun is up, a new study estimates.
The Scientist Speaks Podcast - Episode 11
The Scientist’s Creative Services Team | 1 min read
A Path Back to Health: Immune Tolerance to Infectious Disease
Mosquito with red abdomen and white stripes on human skin
Mosquitoes Add Bacteria to Water to Help Larvae Grow: Preprint
Natalia Mesa, PhD | Apr 12, 2022 | 4 min read
Pregnant mosquito females deploy the microbe Elizabethkingia to speed larval growth; the larvae, in turn, help the bacteria outcompete other strains.
A bright, illuminated, yellow cluster of spheres, representing a mutated base pair, stands out from a double helix of deep red base pairs joined by blue hydrogen bonds
Study: Sickle Cell Mutation Driven by Pressure, Not Random Chance
Dan Robitzski | Mar 17, 2022 | 6 min read
New research finds that the appearance of the HbS mutation, which protects against malaria but leads to sickle cell disease when present in two copies, was more common in sperm samples from men in Ghana, where malaria risk is high, than Europeans.
close-up of a mosquito on human skin
Hope, Concern Surround WHO Green Light of First Malaria Vaccine
Katarina Zimmer | Oct 28, 2021 | 10 min read
RTS,S has several flaws but could still save tens of thousands of lives, experts say.
Red blood cells are pictured in grayscale on a gray background
Red Blood Cells Activate Innate Immune System
Abby Olena, PhD | Oct 20, 2021 | 4 min read
Researchers link the ability of the cells to bind and present DNA from pathogens and cell death to anemia, which is common in COVID-19, and immune activation.
gloved hand holding test tube of blood with a label marking the sample as positive for malaria. There are tubes with lids of various colors in the background.
China Is Malaria-Free, Says World Health Organization
Annie Melchor | Jun 30, 2021 | 2 min read
The certification, a major accomplishment for the world’s most populous nation, may serve as an example to other countries struggling with malaria eradication.
New Malaria Vaccine Shows Most Efficacy of Any to Date: Small Trial
Catherine Offord | Apr 26, 2021 | 3 min read
Immunization had up to 77 percent efficacy in a Phase 2 clinical study of 450 children in Burkina Faso.
A Challenge Trial for COVID-19 Would Not Be the First of Its Kind
Jef Akst | Oct 8, 2020 | 9 min read
Although scientists debate the ethics of deliberately infecting volunteers with SARS-CoV-2, plenty of consenting participants have been exposed to all sorts of pathogens in prior trials.
Infectious Disease Researcher Steve Meshnick Dies
Catherine Offord | Aug 13, 2020 | 3 min read
A leading scientist on the mechanisms of action of antimalarial medications, the University of North Carolina professor made contributions to research and mentoring all around the world.
WHO Halts Hydroxychloroquine Testing Over Safety Concerns
Catherine Offord | May 27, 2020 | 4 min read
A paper published in The Lancet reported that hospitalized COVID-19 patients taking the drug had a higher risk of death, although some researchers have raised questions about the data.
Humans Inoculated with Genetically Modified Malaria Parasites
Ruth Williams | May 20, 2020 | 4 min read
Engineered Plasmodium parasites form the basis of two experimental malaria vaccines that showed safety and encouraging immune responses in clinical trials.
Malaria Parasites’ Biological Clocks Coordinate Cell Destruction
Abby Olena, PhD | May 14, 2020 | 3 min read
Two studies show that Plasmodium—the genus of protozoans that cause malaria—have an internal sense of time that synchronizes with their host’s circadian rhythms and allows the parasites to collectively attack blood cells.
chloroquine hydroxychloroquine covid-19 sars-cov-2 coronavirus trump didier raoult
Journal Publisher Concerned over Hydroxychloroquine Study
Kerry Grens | Apr 9, 2020 | 2 min read
The report by Didier Raoult and colleagues that examined the use of the anti-malarial drug in a small number of COVID-19 patients receives criticism from the very society that published it.
chloroquine hydroxychloroquine covid-19 coronavirus sars-cov-2 malaria antimalarial antiviral
Chloroquine for COVID-19: Cutting Through the Hype
Chris Baraniuk | Mar 20, 2020 | 4 min read
President Donald Trump has touted the drug as a treatment but scientists still don’t know for sure that it is effective in patients. A number of clinical trials aim to find out.
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