Combating Mosquito-Borne Diseases with CRISPR

As alternatives to insecticides, Omar Akbari uses sophisticated genetic engineering methods to solve the world’s mosquito problems.

Written byNiki Spahich, PhD
| 4 min read
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Female mosquitoes are some of the deadliest organisms in the world due to their ability to spread infectious diseases through a simple bite. Mosquito-borne diseases such as yellow fever, Zika, Dengue fever, and malaria kill millions of humans every year, and there are limited therapeutics for their prevention and treatment.

While in college, Omar Akbari worked as a public service intern testing the local mosquito population for human pathogens and eradicating these insects with chemicals. During this experience, he felt dissatisfied with the insecticide-based method of controlling mosquito population and wanted to find a better way to tackle the problem of mosquito-borne disease spread. With a multidisciplinary team in his laboratory at the University of California, San Diego, he now develops tools through genetic engineering techniques such as CRISPR to solve the world’s insect control problems.

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  • Niki Spahich headshot

    Niki Spahich earned her PhD in genetics and genomics from Duke University, where she studied Haemophilus influenzae membrane proteins that contribute to respiratory infections. She later explored Staphylococcus aureus metabolism during her postdoctoral fellowship in the Department of Microbiology and Immunology at the University of North Carolina at Chapel Hill. Prior to joining The Scientist, Niki taught biology, microbiology, and genetics at various academic institutions. She also developed a passion for science communication in written, visual, and spoken forms, which led her to start Science Riot, a nonprofit dedicated to teaching scientists how to communicate to the public through the lens of comedy. Niki is currently the manager of The Scientist's Creative Services Team.

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