CRISPR

A first-of-its-kind gene therapy dramatically reduced misfolded protein levels in some clinical trial participants for up to six months and reduced levels in all participants for up to a year.

The US Patent and Trademark Office has once again decided that the institute has priority over the University of California and collaborators regarding intellectual property rights for CRISPR-Cas9 gene editing in eukaryotes. But the fight over the technique isn’t over.

RNA editing has been in DNA editing’s shadow for nearly a decade, but recent investments in the technology could bring it into the limelight.

Ancient and modern genomes reveal that a variant of the human growth hormone receptor likely helped our ancestors survive when food was scarce.

The results reveal evolutionary relatives of the Cas9 enzyme now used extensively in biotechnology.

The makers of the CRISPR-based testing platform, called miSHERLOCK, say it could enable people at home or physicians in resource-limited environments to detect SARS-CoV-2—and eventually, other pathogens.

In Chapter 6, author Henry T. Greely describes how news of the birth of gene-edited babies rocked a 2018 summit on human genome editing.

CRISPR and other innovations are likely to open up a wealth of new options for how people have children.

Massive extrachromosomal elements named after the hive-minded cyborg villains in Star Trek may be the first of their kind.

The guidance comes after two years of consulting with hundreds of stakeholders, including indigenous peoples, religious leaders, patient groups, and scientists.

The masks contain freeze-dried, cell-free biosensors, enabling them to detect pathogens including SARS-CoV-2.

Senators raise concerns about how Eric Lander of the Broad Institute has handled equality issues.

The physiological demands of that long neck get support from a gene involved in strengthening bones and blood vessels, researchers find after inserting the sequence in mice.