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FTX Collapse Imperils Philanthropic Research Funding
Natural science research projects were among those promised funding by the now-collapsed crypto exchange’s “effective altruism” foundations.
FTX Collapse Imperils Philanthropic Research Funding
FTX Collapse Imperils Philanthropic Research Funding

Natural science research projects were among those promised funding by the now-collapsed crypto exchange’s “effective altruism” foundations.

Natural science research projects were among those promised funding by the now-collapsed crypto exchange’s “effective altruism” foundations.

CRISPR
Illustration of a red bacteriophage infecting a blue bacterium, with other bacteria in the background.
Prokaryotes Are Capable of Learning to Recognize Phages
Patience Asanga | Aug 17, 2022 | 3 min read
Immune defense genes in bacteria and archaea can identify viral proteins, a study finds, revealing similarities between the immune systems of prokaryotic and eukaryotic organisms.
A gloved hand holds a tweezer and pulls a section of DNA away from a double helix
First Person Dosed in Novel Gene Editing Clinical Trial
Amanda Heidt | Jul 12, 2022 | 4 min read
The biotech company Verve Therapeutics launched the study with the aim of using base editing to treat a genetic condition that causes high cholesterol and increases a person's risk of developing cardiovascular disease.
COVID-19: Lessons Learned
COVID-19: Lessons Learned
The Scientist Creative Services Team | 2 min read
An expert panel will discuss what researchers have learned from the COVID-19 pandemic and what lessons remain for the future. 
Logo for The Scientist's 2022 Top 10 Innovations
Last Chance to Enter Our Annual Top 10 Innovations Contest
The Scientist Staff | Jul 11, 2022 | 1 min read
There is only one week remaining to submit your new product to vie for a coveted spot in The Scientist’s 2022 competition.
Green-tinged image of fly eye with shiny and black portions
New CRISPR Technique Causes Few Unintended Mutations in Fruit Flies
Jason P. Dinh | Jul 1, 2022 | 4 min read
A study finds that CRISPR-Nickase, which changes just one allele of a given gene, improves gene editing efficiency compared with CRISPR-Cas9.
Mosquito on leaf stock photo
Combating Mosquito-Borne Diseases with CRISPR
Niki Spahich, PhD | 4 min read
As alternatives to insecticides, Omar Akbari uses sophisticated genetic engineering methods to solve the world’s mosquito problems.
an artistic rendering of CRISPR/Cas9
Ten Years of CRISPR
Sophie Fessl | Jun 28, 2022 | 7 min read
This month marks ten years since CRISPR-Cas9 was repurposed as a gene editing system, so we’re looking back at what has been accomplished in a decade of CRISPR editing.
A cockroach clings to the inside of a white mug.
Injecting Cockroaches with CRISPR Gene Edits Their Offspring
Sophie Fessl | May 25, 2022 | 4 min read
A new method has allowed researchers to conduct the first gene knock-out and knock-in edits on cockroaches and may extend to many other insects.
3D representation of a DNA helix and with a base offset from the main helix, illustrating the concept of base editing.
A CRISPR Alternative for Correcting Mutations That Sensitize Cells to DNA Damage
Deanna MacNeil, PhD | 3 min read
Researchers turned to base editors to correct mutations causing the rare genetic disease Fanconi anemia without inducing double-strand DNA breaks.
close-up of an Aedes aegypti mosquito on human skin
Researchers Discover What Attracts Mosquitoes to Humans
Sophie Fessl | May 11, 2022 | 5 min read
A brain area of Aedes aegypti responds specifically to components of human sebum, a study finds.
An orange CRISPR Cas 9 enzyme cutting DNA
CRISPR-Based Treatment Successfully Lowers Toxic Protein Levels
Natalia Mesa | Mar 2, 2022 | 3 min read
A first-of-its-kind gene therapy dramatically reduced misfolded protein levels in some clinical trial participants for up to six months and reduced levels in all participants for up to a year.
3d render illustration of Single strand ribonucleic acid.
Message in a Bottle: Developing mRNA Therapeutics
The Scientist Creative Services Team and Mirus Bio | 3 min read
A high efficiency, low toxicity method for direct RNA delivery into cells.
Vector illustration of a courthouse with test tubes as pillars
CRISPR Patent Ruling Favors Broad Institute
Jef Akst | Mar 1, 2022 | 3 min read
The US Patent and Trademark Office has once again decided that the institute has priority over the University of California and collaborators regarding intellectual property rights for CRISPR-Cas9 gene editing in eukaryotes. But the fight over the technique isn’t over.
DNA
In Editing RNA, Researchers See Endless Possibilities
Christie Wilcox | Dec 1, 2021 | 10+ min read
RNA editing has been in DNA editing’s shadow for nearly a decade, but recent investments in the technology could bring it into the limelight.
spatial CRISPR screen for cancer
A Brave New World for Spatial Genomics in Cancer Research
Nele Haelterman, PhD | 3 min read
A new CRISPR screening technology allows scientists to recreate tumor heterogeneity in vivo and study how it affects all aspects of cancer biology.
group of paleolithic people around a campfire
Gene Variant Points to Starvation’s Evolutionary Legacy
Sophie Fessl | Sep 28, 2021 | 4 min read
Ancient and modern genomes reveal that a variant of the human growth hormone receptor likely helped our ancestors survive when food was scarce.
cartoon depiction of a pair of scissors about to cut a DNA double helix
Researchers Uncover New Families of Gene-Editing Enzymes
Annie Melchor | Sep 15, 2021 | 2 min read
The results reveal evolutionary relatives of the Cas9 enzyme now used extensively in biotechnology.
Technique Talk: Understanding Cancer One Base Edit at a Time
Technique Talk: Understanding Cancer One Base Edit at a Time
The Scientist Creative Services Team | 1 min read
Francisco J. Sánchez-Rivera will discuss strategies to design CRISPR base editor libraries for in vivo applications.
photograph of miSHERLOCk device against a white background
A Self-Contained COVID-19 Test with 3-D Printed Parts
Annie Melchor | Aug 11, 2021 | 7 min read
The makers of the CRISPR-based testing platform, called miSHERLOCK, say it could enable people at home or physicians in resource-limited environments to detect SARS-CoV-2—and eventually, other pathogens.
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