Increasing mitochondrial activity in worms by engineering a light-activated proton pump into the organelle’s membrane extends the animals’ lifespan without evidence of health decline, according to a preprint.

A first-of-its-kind gene therapy dramatically reduced misfolded protein levels in some clinical trial participants for up to six months and reduced levels in all participants for up to a year.

A study shows “sonogenetics” could be a useful new tool in neuroscience and other fields.

The procedure, performed last Friday, is a milestone in a long effort to boost the number of organs available for safe transplantation.

Immune-response levels to the edible vaccine varied among the subjects, possibly due to differences in the gut microbiome.

The decision, which concerns the removal of a sugar molecule on the surface of cells in a line of domestic pigs, marks the first time an approval has been granted for both purposes simultaneously.

Harvey Alter, Michael Houghton, and Charles Rice share the Physiology or Medicine award for their contributions to identifying the virus and demonstrating that it was responsible for hepatitis among blood transfusion recipients.

There have been no reports of health or environmental harm in other locations where genetically modified mosquitoes have been introduced over the last decade.

Engineered Plasmodium parasites form the basis of two experimental malaria vaccines that showed safety and encouraging immune responses in clinical trials.

Researchers are engineering microbes to deliver therapeutics specifically to tumors, maximizing the treatments’ efficacy while minimizing side effects.

Autonomous, living microrobots that seek and destroy cancer are not as futuristic as one might imagine, thanks to a fusion of robotics and synthetic biology.

The genetically modified bacteria spark an RNAi response in the parasite that leads to self-destruction—and perhaps a path to combatting colony collapse disorder.

The biotech Oxitec had released the genetically engineered insects with the hope that they would breed with wild populations and produce offspring that die young. But that’s not always happening.

Genetic engineers have co-opted base editing machinery to enable information storage and processing in the DNA of bacterial and mammalian cells.

The fast-growing fish can now be raised and sold in the US, although it’s likely to be some time before the product hits the market.

The large-scale experiments aim to test how the technology would fare in the wild, if deployed to knock down populations of the pests.

Adenine editing enzymes have been adapted for use in plants.