Applied Bio and Orchid Target Forensics Labs

Determining the identity of a person through a DNA sample is rarely straightforward, especially if the sample comes from a decomposed, burned, or otherwise degraded source. A body that has been submerged under water for months, for example, may contain DNA fragments that are too small to be analyzed by conventional means. Two companies, Foster City, Calif.-based Applied Biosystems http://www.appliedbiosystems.com, and Princeton, NJ-based Orchid Biosciences http://www.orchid.com, have worked out

Written byAileen Constans
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Determining the identity of a person through a DNA sample is rarely straightforward, especially if the sample comes from a decomposed, burned, or otherwise degraded source. A body that has been submerged under water for months, for example, may contain DNA fragments that are too small to be analyzed by conventional means. Two companies, Foster City, Calif.-based Applied Biosystems http://www.appliedbiosystems.com, and Princeton, NJ-based Orchid Biosciences http://www.orchid.com, have worked out methods to deal with such samples.

Applied Biosystems' new Quantifiler™ Human DNA and Y Human Male DNA Quantification kits enable investigators to rapidly determine if a sample contains DNA suitable for conventional analysis. Designed for real-time PCR (RT-PCR) quantification of DNA in a sample, the kits use automation to reduce hands-on time, says associate product manager Karen Cormier. And, because the technique is PCR-based, the kits provide a more comparable indicator of how much of the DNA in the sample can ...

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