Graphic: Courtesy of Peter Haebel
 RIBOSOME REVEALEDA view of the active site of the large ribosomal subunit. Proteins of this large assembly are shown in yellow; the ribosomal RNA is in gray.

Scientifically speaking, the ribosome's make-up and raison d'etre is elementary: Composed of RNA and proteins, it's the cell site where amino acids get strung together to form new proteins. And, while protein synthesis is a well-studied cellular process, says Nenad Ban, assistant professor, Institute for Molecular Biology and Biophysics, Swiss Federal Institute of Technology, Zurich, "most ribosomal studies in the past were done 'blindly' since no high-resolution structural information on the ribosome was available."

Data derived from the Science Watch/Hot Papers database and the Web of Science (ISI, Philadelphia) show that Hot Papers are cited 50 to 100 times more often than the average paper of the same type and age.

N. Ban, P. Nissen, J....

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