Elie Dolgin
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Articles by Elie Dolgin

Video journal goes closed access
Elie Dolgin | | 2 min read
The__ linkurl:Journal of Visualized Experiments;http://www.jove.com __(JoVE), the first life sciences video methods journal, moved from an open access publishing model to paid subscription status last week (Apr. 2) in order to cover its costs of operations. The journal, which has released more 300 video-protocol "articles," had been open access since its launch in October 2006. But citing the higher than usual costs associated with video production and the supporting technological infrastructur

Brain diseases are genomic opposites
Elie Dolgin | | 2 min read
Autism and schizophrenia may be two sides of the same genomic coin. Copy number variations in the exact same genes determine whether patients suffer from one condition or the other, according to data presented on Friday (Apr. 3) at the linkurl:Sackler Colloquium on Evolution in Health and Medicine;http://www.nasonline.org/site/PageServer?pagename=Sackler_Evolution_Health_Medicine in Washington, DC. Both autism and schizophrenia involve disturbances in brain areas linked to social functions, bu

Human fertility gene found
Elie Dolgin | | 3 min read
Researchers have for the first time identified a gene that boosts fertility in humans. A single amino acid substitution in a gene linked with cystic fibrosis may be responsible for the differential reproductive success of some men living in a religious community in the US prairies, according to data presented yesterday (Apr. 2) at the linkurl:Sackler Colloquium on Evolution in Health and Medicine;http://www.nasonline.org/site/PageServer?pagename=Sackler_Evolution_Health_Medicine in Washington, D

Stem cell rat race
Elie Dolgin | | 3 min read
Rat embryonic stem cells were used to construct a chimeric animal (inset), shown here with two of his pups. Credit: Above: Courtesy of Ping Li and Qi-Long Ying Inset: Courtesy of John Agnew" />Rat embryonic stem cells were used to construct a chimeric animal (inset), shown here with two of his pups. Credit: Above: Courtesy of Ping Li and Qi-Long Ying Inset: Courtesy of John Agnew In 1981, Martin Evans and Matthew Kaufman, wor

Septic sperm
Elie Dolgin | | 3 min read
Toxin-affected dead worm embryos and their antidote-carrying siblings. Credit: Courtesy of Hannah Seidel" />Toxin-affected dead worm embryos and their antidote-carrying siblings. Credit: Courtesy of Hannah Seidel In 2006, Hannah Seidel, a graduate student in Leonid Kruglyak's lab at Princeton University, performed an experiment that hundreds of C. elegans biologists had done before: She crossed two c

Cancer's culprit
Elie Dolgin | | 4 min read
Breast cancer's genetic profile calls the cancer stem cell hypothesis into question.

Astute algae, conned corals
Elie Dolgin | | 3 min read
Coral reefs form as a partnership between sea anemone-like polyps and photosynthetic algae that provides nutrients for the former and safe, well-lit shelter for the latter. But this alliance might not start off as a true joint venture. New research published online earlier this month in__ linkurl:Molecular Ecology;http://www3.interscience.wiley.com/journal/122268905/abstract __indicates that symbiotic algae sneak inside coral cells in a stealth manner, rather than being actively welcomed by thei

Texas school hired while firing
Elie Dolgin | | 4 min read
The University of Texas Medical Branch in Galveston is bringing in new assistant professors at the same time as around 30 fired faculty members, many of them tenured, fight for the jobs they lost in the aftermath of Hurricane Ike. After the Sept. 13 storm hit the island campus, UTMB declared financial exigency and linkurl:conducted mass layoffs;http://www.the-scientist.com/blog/display/55255/ that ultimately cost around 2,500 jobs, including the posts of linkurl:127 faculty members,;http://txfa

Pluripotency via plasmids
Elie Dolgin | | 3 min read
Researchers are one step closer to reprogramming stem cells that are safe for use in the clinic with a new virus-free method for deriving human induced pluripotent stem (iPS) cells that doesn't rely on integrating foreign DNA, according to a linkurl:study;http://www.sciencemag.org/cgi/content/abstract/1172482 published online today in __Science__. Skin cells induced to a pluripotent stateImage: Junying Yu / UW-MadisonSince these cells' genomes have never been genetically modified, they provide

EU animal research under fire
Elie Dolgin | | 2 min read
New proposed European laws to harmonize animal research across the EU could seriously hamper biomedical research, according a linkurl:report;http://www.esf.org/emrc/pdpasp published yesterday (Mar. 24) by the European Science Foundation (ESF) and a linkurl:declaration;http://www.understandinganimalresearch.org.uk/policy_issues/european_regulation/uk_bioscience_sector_declaration issued today (Mar. 25) by a group of leading British life sciences organizations. Image: Understanding Animal Researc

India debates open access
Elie Dolgin | | 4 min read
India's premier publicly-funded research organization is pushing to make all research published at its institutions open access. But its pleas are falling on deaf ears, critics say, as individual laboratories have been slow to take up the charge. Image: India MostLast month (Feb. 6), the head of research and development planning at India's linkurl:Council of Scientific and Industrial Research;http://www.csir.res.in/ (CSIR), linkurl:Naresh Kumar,;http://www.jst.go.jp/astf/document3/CV%20Naresh%

Flagellar friendship
Elie Dolgin | | 2 min read
A bacterium found in sewage sludge uses its tail-like flagellum to lasso a symbiotic archaeon and keep it close at bay so that the two microbial partners can synchronize their metabolism, a Japanese research team reports in the Mar. 20 issue of __Science__. Scanning electron micrograph ofPelotomaculum thermopropionicumImage: PNNLThe paper is "important for understanding how organisms that are so incredibly different, at least phylogenetically, are able to cooperate," linkurl:Joseph Grzymski,;ht












