3D structural model of a Cas protein and sgRNA targeting and unwinding DNA for gene editing.

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Researchers create and improve CRISPR-Cas mediated gene editing technologies based on prokaryotic CRISPR systems and eukaryotic DNA repair mechanisms.

CRISPR Gene Editing: Cas9 and Beyond

Brush Up Summaries

Abstract rendering of a tumor and its microenvironment in purple

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Graphic of a tumor and the tumor microenvironment, showing various immune cells, cancer cells, extracellular matrix, blood vessels, and a hypoxic area.

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Learn about the tumor microenvironment (TME), a key influencer of cancer growth, spread, and treatment success.

The Basics of the Tumor Microenvironment

Jennifer Philips, an infectious disease researcher and physician at Washington University in St. Louis, investigates Mycobacterium tuberculosis. She and Ekansh Mittal, an instructor in the same institution, wear laboratory coats and are seated. An image of bacterial cells can be seen in a computer screen on the background.

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A group of people in a laboratory. Lab equipment is seen on the bench.

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Red blood cells infected with Plasmodium falciparum parasites.

Immune cells are labeled with a red marker. HIV particles (green) from an infected cell are transferred to an uninfected cell via direct cell-to-cell contact.

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Cells infected with the pathogen Mycobacterium tuberculosis.

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Olivier Schwartz, a virologist at the Pasteur Institute, studies HIV and other human pathogenic viruses. He wears a gray pullover and glasses.

The human Microbiome, the genetic material of all the microbes that live on and inside the human body.

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The Art of Microbial Disguise

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A stylized futuristic outline of a human brain.

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Front and side views of Ultima Genomics&rsquo; UG100 genome sequencing platform.

ThinkCyte&rsquo;s VisionSort multi-laser flow cytometer

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Meteor Biotech&rsquo;s CosmoSort spatial cell sorter

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cosmosort

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A photo depicting the contents of the CRISPR in a Box kit.

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PhysioMimix&reg; Single-Organ Higher Throughput (HT) System

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A photo of a scientist loading their prepared library into a flow cell docked within the MinION device.

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2024 Top 10 Innovations logo with a cartoon of a head with a super-imposed light blub

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Image representing how the STARVUE program analyzes stained tissue

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2024 Top 10 Innovations

Graphic of a robot inspecting information.

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Photo of Dror Kolodkin-Gal pointing at a section of an AI-generated image on a screen.

Detection or Deception: The Double-Edged Sword of AI in Research Misconduct

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New artificial intelligence tools help scientists fight back against a rising tide of research misconduct, but is it enough?

A reimagined lipid vehicle for nucleic acids could overcome the limitations of current vectors. 

3D illustration of a gold lipid nanoparticle with pink nucleic acid inside of it. Purple and teal spikes stick out from the lipid bilayer representing polyethylene glycol.

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A Nanoparticle Delivery System for Gene Therapy

Johanna Pruller, PhD 

tecan

Multiomics platform streamlines workflows and provides real-time insights, optimizing resource usage and ensuring smooth, data-driven operations

Tecan introduces Veya: bringing digital, scalable automation to labs worldwide

Explore a Concise Guide to Optimizing Viral Transduction

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Takara Bio

Learn how to overcome the challenges of viral transduction workflows.

A Visual Guide to Lentiviral Gene Delivery

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Inventia Life Science, an innovator in 3D cell culture technologies, announces the launch of RASTRUM&trade; Allegro, a groundbreaking advancement in 3D cell culture technology designed to accelerate drug discovery and disease research with unprecedented scalability, reproducibility, and efficiency.

Inventia Life Science Launches RASTRUM&trade; Allegro to Revolutionize High-Throughput 3D Cell Culture for Drug Discovery and Disease Research

An illustration of differently shaped viruses.

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Twist Bio

Twist Bioscience

Learn how a target enrichment approach improves the discovery and characterization of viral pathogens.

Detecting Novel Viruses Using a Comprehensive Enrichment Panel

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Considerations for Cell-Based Assays in Immuno-Oncology Research

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In this webinar, Ethan Shelkey and Aurita Menezes will highlight key aspects in the design of cell-based assays.

An illustration of animal and tree silhouettes.

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Discover how alternative animal models provide new perspectives on physiological and biochemical processes.

From Water Bears to Grizzly Bears: Unusual Animal Models

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Experts from the Women&rsquo;s Brain Foundation and bit.bio will explore the importance of sex-specific in vitro models for neurological research and drug discovery.

Sex Differences in Neurological Research

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Discover how scientists are designing the next groundbreaking vaccines against infectious diseases.

Johanna Pruller, PhD

Articles by Johanna Pruller, PhD

CRISPR Gene Editing: Cas9 and Beyond

The Basics of the Tumor Microenvironment

A Nanoparticle Delivery System for Gene Therapy

Research Resources

Podcasts

Webinars

Videos

Infographics

eBooks

Considerations for Cell-Based Assays in Immuno-Oncology Research

From Water Bears to Grizzly Bears: Unusual Animal Models

Sex Differences in Neurological Research

New Frontiers in Vaccine Development

Products

Product News

Tecan introduces Veya: bringing digital, scalable automation to labs worldwide

A Visual Guide to Lentiviral Gene Delivery

Inventia Life Science Launches RASTRUM™ Allegro to Revolutionize High-Throughput 3D Cell Culture for Drug Discovery and Disease Research

Detecting Novel Viruses Using a Comprehensive Enrichment Panel