Articles by John Borchardt

As HIV continues to develop resistance to the present antiretrovirals a new class of drugs offer hope for the treatment of AIDS.

The US Animal Welfare Act for humane care of research animals excludes rats, mice and birds. Efforts to remedy this are in progress.

A new research centre is being established in Singapore that will use a multidisciplinary approach to study systems biology.

Vitamin C could promote production of DNA-damaging compounds and may help explain why vitamin C has thus far shown little effectiveness at preventing cancer in clinical trials.

The world's most powerful, high-resolution nuclear magnet resonance spectrometer provides researchers with the ability to determine structures of high molecular weight proteins and nucleic acids with much greater sensitivity and resolution.

can quickly become resistant to linezolid during extended treatment.

The recent American College of Cardiology meeting provided a striking example of how the new technology of combinatorial chemistry is changing the face of the drugs market.

In a bid to rival San Diego and Boston as a centre for biomedical research and technology transfer, Houston has just announced the $633 million, 64-acre Southeast Texas Biotechnology Park.

The German government has just announced a $425 million, three-year genome research funding program. This type of government support, and the revision of federal laws are promoting a growth spurt in the German biotechnology industry.

res at a daily treatment cost of less than one dollar.

US FDA user fees may have accelerated new drug development but a recent survey suggests difficulties in obtaining volunteers for human clinical trials still slow progress.

Bristol-Myers Squibb's novel patent strategy could prove effective in protecting its marketing exclusivity for the blockbuster anxiety drug BuSpar.

To increase research on minority health problems, the US government has established the National Center on Minority Health and Health Disparities.

Age-related macular degeneration (AMD) is the leading cause of blindness in individuals over 55 years of age in the developed world. AMD affects about 11 million Americans, 5 million of whom have become legally blind because of it. Stargardt's macular degeneration (STGD3) is an early-onset form of AMD that affects about 30,000 children and young adults in the United States. Researchers reported in this week's Nature Genetics that they have identified a gene linked to AMD and predicted the discov

A French research team is criticised for allowing a clinical trial to continue even though preliminary results suggested the drug therapies were ineffective.