Jorge Cortese
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Articles by Jorge Cortese

Array of Options
Jorge Cortese | | 10 min read
Instrumentation for Microarray Production and Analysis - Part 1 Instrumentation for Microarray Production and Analysis - Part 2 Nanogen's NanoChip™ Cartridge Today's molecular biology era can be defined by the dictum, "So many genes, so little time," and technologies for gathering genetic information are gaining speed. DNA microarrays are one of the most promising answers to that cry. DNA microarrays are glass microslides or nylon membranes containing DNA samples (genomic DNA, cDNA,

Sphere of Influence
Jorge Cortese | | 2 min read
Luminex's unique microsphere addressing system In the past, a researcher bragging about running 100 different assays per minute in a single test tube might be counseled to get some sleep and stop breathing hazardous fumes. LabMAP (Laboratory Multiple Analyte Profiling) technology developed by Luminex Corp. of Austin, Texas, now makes such claims possible and miraculously expands analytical assay development. Luminex uses a proprietary dyeing process to label polystyrene microspheres with p

Let It Shine
Jorge Cortese | | 9 min read
Fluorescence Detection Products Courtesy of BD PharMingenMulticolor immunofluorescent cell staining showing cell surface FITC (green) staining and intracellular PE (orange) and APC (red) staining. Is radioactive detection of biomolecules destined to the same fate as the Berlin Wall? The multitude of nonisotopic detection methods now available suggests that the 21st century may come to be billed as the "nonisotopic research century." The broadest common denominator of this up and coming cast of

Getting to Megabase
Jorge Cortese | | 7 min read
Large Fragment Cloning Products and Services Gone are the days when all you had to do to get out of grad school was identify and clone a new gene. Besides, with the information rapidly gathered through the Human Genome Project, there will soon no longer be a "new gene." Enormous projects such as sequencing entire genomes have created a need to play with bigger pieces of the puzzle, and a new universe of technologies adapted to large DNA fragments has appeared. Assignment of a new gene to a par

The X-Treme Sport Of Drug Screening: Xpress-Screen Assay Achieves Quantitative Detection of mRNA For Drug Discovery
Jorge Cortese | | 2 min read
Image provided by PE Biosystems Advanced Discovery Sciences Xpress-Screen detection system In high-throughput screening (HTS)-based drug discovery, the task is to create and read enormous libraries, seeking the rare lead that eventually becomes a multibillion-dollar drug. No stone is left unturned in this search, and a multitude of single-molecule detection assays is lined up for every program direction imaginable. Xpress-Screen combines Tropix Inc.'s chemiluminescence technology with the we










