Articles by Kenneth Lee

The amygdala enhances our perception of stimuli that have emotional significance.

-calcium-calmodulin kinase II is required for consolidation of memory.

Despite huge variations in brain size, mammalian groups are characterised by relatively constant brain proportions.

In the 3 May Nature, Fred Gage and colleagues of the Salk Institute in La Jolla, California report the successful isolation and propagation of neural progenitor tissue from post-mortem brain tissue (Nature 2001, 411:42-43).Two hours post mortem brain tissue was removed from an 11-week-old neonate and a 27-year-old adult. The samples were placed in cold antibiotic-containing Hank's buffered salt solution and processed for cell culture 3 hours later. Representative sections of the hippocampus, ven

In the 3 May Nature Oliver Guillin and colleagues report that the expression of the dopamine D3 receptor is regulated by the brain-derived neurotrophic factor (BDNF), a protein once thought to be needed simply for the proliferation and survival of neurons (Nature 2001, 411:86-89).D3 receptors are expressed mainly in an area of the brain known as the shell of the nucleus accumbens. Neurons from the ventral tegmental area (VTA), which produce both dopamine and BDNF, connect to neurons of the nucle

A mouse strain has been generated in which K-ras alleles are activated at random, mimicking the sporadic occurrence of K-ras mutations in human cancers.

Three independent studies quash the theory that experimental polio vaccines administered in Central Africa in the 1950s were the origin of the AIDS pandemic.

Sites of injury to the central nervous system can be treated with chondroitinase ABC to clear the path for axon regeneration.

encodes a molecule that helps guide axons from the eye to the brain.

Honeybees are capable of cognitive performances thought to occur only in vertebrates.

The enzyme ATP synthase spins like a wheel to convert energy into ATP for storage. High-speed imaging reveals the details of the rotation.

may help explain how this malarial parasite maintains a chronic infection.

Mice in which the gene for the cannabinoid receptor has been knocked out eat less than normal.

Plants have evolved a number of cold-response genes encoding proteins that induce tolerance to freezing, alter water absorption and initiate many other low temperature induced processes. In the 1 April Genes and Development, Jian-Kang Zhu and colleagues of the Department of Plant Sciences, University of Arizona, shed light on how these genes are regulated.Lee et al report that the protein HOS1 negatively regulates cold-response genes in Arabidopsis. At low temperatures, HOS1 relocalises from the

might be able to differentiate between real and imagined fear.