Linda Raab
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Articles by Linda Raab

An Integrated Approach to Fluorescence Imaging
Linda Raab | | 3 min read
Image: Courtesy of TILL Photonics TILLvisDECO in action. Image before (middle) and after (right) deconvolution. The quality of the data obtained from fluorescence imaging studies depends on the system of components used to acquire, analyze, and process the fluorescent images. As an alternative to building a system piecemeal, using components from several vendors, TILL Photonics of Gräfelfing, Germany, offers its fully integrated TILLvisION system and software modules for fluorescenc

Simple Complexes
Linda Raab | | 2 min read
As an alternative to the standard chemical methods for antibody conjugate preparation, Molecular Probes of Eugene, Ore., recently introduced its Zenon™ technology for direct labeling of primary antibodies. Instead of using covalent modification, Zenon technology relies on immune complexes to create antibody conjugates. The first Zenon product line, Zenon One, provides a variety of reagent kits for labeling mouse IgG1 isotype antibodies with a particular detection label. Zenon technology d

A Sharper Fluorescent Image
Linda Raab | | 2 min read
Accurate fluorescence microscopic imaging of three-dimensional specimens is often impaired by the signal distortion that occurs as specimen light travels through the optical system to the observing camera. Thornwood, NY-based Carl Zeiss Microimaging Inc.'s powerful 3D Deconvolution software reassigns out-of-focus light back to its original location utilizing a generic mathematical algorithm, which greatly improves the image's resolution and signal-to-noise ratio.1 How a particular optical syst

Cultural Revolution: Mycoplasma Testing Kits and Services
Linda Raab | | 9 min read
Date: October 11, 1999Mycoplasma Detection Kits Mycoplasma Testing Services Most scientists who engage in cell culture find it such a chore to split cells on a regular basis that conscientious habits like routine testing for mycoplasma remain an unrealized ideal. Although mycoplasma contamination can potentially foil the most crucial of experiments, one may argue that mycoplasma testing is expensive, time consuming, or complicated. Fortunately, times are changing. Several companies have develop

Easy as Y
Linda Raab | | 3 min read
NUNC™ Brand EasY Flask from Nalge Nunc Designing the next generation of cell culture flasks would seem a difficult task. How can one improve upon a rather standard laboratory technology? Nalge Nunc International Corporation (a subsidiary of Sybron International) has answered that question with the new NUNC™ Brand EasY Flask product line, which incorporates three new design features: a large-aperture neck opening, allowing greater access to the growth surface; a quick-turn mechanism

Maximize In Vitro Culture Possibilities
Linda Raab | | 4 min read
From Redmond, et al., "Perfused transcapillary smooth muscle and endothelial cell co-culture--a novel in vitro model," In Vitro Cellular & Developmental Biology--Animal, Volume 31:601-609. Copyright 1995 by the Society for In Vitro Biology. Reproduced with permission of the copyright owner. The Cellmax™ culture system uses hollow fiber bioreactor technology in applications as diverse as secreted protein production, lymphocyte expansion, and cellular co-cultivation. The concept of

The 'E' means 'Easy': Invitrogen's E-Gel Precast Agarose Electrophoresis System
Linda Raab | | 3 min read
E-Gel from Invitrogen As laboratory personnel search for more streamlined protocols to maximize daily productivity, commercial vendors are designing a new family of convenience products. Premixed buffer stocks, minicolumns to isolate plasmid DNA, and even agar plates prepared using premeasured capsules have all allowed researchers to focus their efforts on experimental design rather than on laborious preparative tasks. To add to the growing list of such products is the new E-Gel™ from Inv
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