Methylation at regulatory regions, especially promoters, correlates with transcriptional activity: Sequences near silent genes generally are methylated, whereas those near active regions are not.

Genes active at time of Xenopus nuclei transfer are also overexpressed in cloned embryos

Presence in developmental genes may underlie evolution of morphological diversity

Unlike its genomic, proteomic, and transcriptomic predecessors, a comprehensive glycome project (see "Sugars get an 'ome of their own," 18[15]:45–7, Aug. 2, 2004) may have to include telescopes and spacesuits. Last month, astronomers announced that they've detected sugar molecules in the coldest gas and dust clouds of the central Milky Way. The intensity of the signal was surprisingly strong, hinting that these clouds, the birthplace of stars and planets, may also be churning out the build

Study finds that retrotransposition sped up glutamate metabolism in ape and human brains

Fly lifespan is boosted by early exposure to bacteria, but curbed by presence late in life

Study shows that synonymous codon usage varies in human tissues, perhaps due to evolution

Stiff structure of centromere protein may ensure faithful chromosome inheritance