Chemokines and their receptors help direct cell migration to sites of inflammation. You heard it here--chemokine receptors and ligands are in. Inflammation, cancer, asthma, rheumatoid arthritis, angiogenesis, and AIDS are just a few areas in which chemokines and their receptors are crucial. Therefore, chemokine pathways represent potentially valuable therapeutic targets. Asthma, one of the most common chronic diseases in the industrialized world, is recognized as an inflammatory disease, and ste

Dishes, Flasks and Roller Bottles. Plates Sarstedt's tissue culture dishes A cell is considered cultured once it can adhere to a substrate or remain in suspension and proliferate. A primary culture is derived either from an outgrowth of migrating cells from a tissue fragment or from mechanically or enzymatically dissociated tissue. Monolayer cells capable of proliferation will grow to confluence, and cells that are contact inhibited will stop growing at a certain cell density. Transformed cells

Date: October 11, 1999Table of CO2 Incubators VWRbrand large-capacity CO2 incubator, model 1927 There would the new "golden age of biology" be without the millions of cells that are used to unlock the mysteries of life? Maintaining cell culture stocks is essential and cannot be accomplished without the proper environmental controls. Once the cells are fed and properly seeded to the correct density, they require precise heat, humidity, and gas levels to thrive. Investigators sleep at night ent

Date: September 13, 1999Cell Separation Products Magnetic Cell Separation Technologies that isolate rare cell types to high purity are essential to the cell biology researcher. Understanding cell developmental pathways becomes increasingly significant as diagnosis and treatment of disease turns more to the molecular level.1 This diagnosis of cell-related diseases requires methods for detection, isolation, and analysis of individual cells regardless of their frequency.2 The hematopoietic system

In the rush to sequence every gene in existence researchers need to increase their capacity and throughput. However, the ability to sequence samples quickly is fruitless if the quality of the DNA is poor. Sequencing of double-stranded DNA can complicate the process because it may produce a less clean read-through of the gene fragment of interest than a single-stranded starting template would. On the other hand, manual preparation of single-stranded DNA can be time consuming and result in decrea