Date: September 13, 1999Cell Separation Products Magnetic Cell Separation

Technologies that isolate rare cell types to high purity are essential to the cell biology researcher. Understanding cell developmental pathways becomes increasingly significant as diagnosis and treatment of disease turns more to the molecular level.1 This diagnosis of cell-related diseases requires methods for detection, isolation, and analysis of individual cells regardless of their frequency.2 The hematopoietic system has provided an easily accessible model for studying the processes that regulate cell growth. Accessibility isn't everything, however, as the most primitive cells and their progeny are present at relatively low levels. To further complicate matters, no unique, stable phenotype has been discovered to permit the activities of these cells to be assayed directly.3 Functional assays to study developmental pathways take weeks to complete, which could be the difference between a novel discovery and a "me too" paper.

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