Automated Microscopy Gets a New Shape

Courtesy of TILL PhotonicsRainer Uhl, CEO of Gräfelfing, Germany-based TILL Photonics http://www.till-photonics.com, laments that while the field of microscopy has evolved dramatically over the last century, the classical light microscope itself has not. New applications such as confocal and multiphoton microscopy were adapted to the microscopes rather than vice versa, placing constraints on the user.Uhl and colleagues, in cooperation with the BioImaging Zentrum of the University of Munich,

| 2 min read

Register for free to listen to this article
Listen with Speechify
0:00
2:00
Share

Courtesy of TILL Photonics

Rainer Uhl, CEO of Gräfelfing, Germany-based TILL Photonics http://www.till-photonics.com, laments that while the field of microscopy has evolved dramatically over the last century, the classical light microscope itself has not. New applications such as confocal and multiphoton microscopy were adapted to the microscopes rather than vice versa, placing constraints on the user.

Uhl and colleagues, in cooperation with the BioImaging Zentrum of the University of Munich, adopted a different approach, redesigning the tool to fit the method. "We said, let's take all the known applications together, distill the essence of what microscopy is or will be, and try to design something which reduces the microscope to its essential, the objective," says Uhl. TILL's designers therefore placed the objective in the middle of the device, maximizing the optical path's accessibility.

The result is the iMIC, a motorized, automation-ready, octagonal platform with a central objective lens and optical ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Meet the Author

  • Aileen Constans

    This person does not yet have a bio.

Published In

Share
May digest 2025 cover
May 2025, Issue 1

Study Confirms Safety of Genetically Modified T Cells

A long-term study of nearly 800 patients demonstrated a strong safety profile for T cells engineered with viral vectors.

View this Issue
iStock

TaqMan Probe & Assays: Unveil What's Possible Together

Thermo Fisher Logo
Meet Aunty and Tackle Protein Stability Questions in Research and Development

Meet Aunty and Tackle Protein Stability Questions in Research and Development

Unchained Labs
Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Bio-Rad
How technology makes PCR instruments easier to use.

Making Real-Time PCR More Straightforward

Thermo Fisher Logo

Products

The Scientist Placeholder Image

Biotium Launches New Phalloidin Conjugates with Extended F-actin Staining Stability for Greater Imaging Flexibility

Leica Microsystems Logo

Latest AI software simplifies image analysis and speeds up insights for scientists

BioSkryb Genomics Logo

BioSkryb Genomics and Tecan introduce a single-cell multiomics workflow for sequencing-ready libraries in under ten hours

iStock

Agilent BioTek Cytation C10 Confocal Imaging Reader

agilent technologies logo