One thing's certain at the Keystone Symposia on linkurl:Structural Genomics; and linkurl:Frontiers in Structural Biology; running this week in Keystone, Colorado: there's some seriously big science going on in the world of structural biology. Aled Edwards of the University of Toronto rattled off the program goals of the linkurl:Structural Genomics Consortium; (SGC), of which Edwards is the chief executive: 50 structures solved between July 2004 and June 2005; 112 structures in '05-'06; and 224 in '06-'07. Does that sound laughable? Hardly. With facilites at the universities of Toronto and Oxford and the Karolinska Institute, the consortium has since its inception solved some 180 structures at an average $125,000 per. The linkurl:RIKEN Genomic Sciences Center; is putting up even bigger numbers. According to project director Shigeyuki Yokoyama, the Center, with some 40 NMRs (including 3 900-Mhz instruments and 14 800s), solved 1,347 structures between April 2002 and October 2005, 700 of...

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