Brain-Machine Interface Training Triggers Recovery

Researchers studying the use of neural prosthetics in paralyzed patients describe the approach’s therapeutic potential.

Written byBob Grant
| 3 min read

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Hypothesis for mechanism of neurological improvement in spinal cord injury patientsA.R.C. DONATI ET AL., SCIENTIFIC REPORTSParaplegic patients who regularly trained with brain-machine interfaces (BMI) to walk in a virtual world or articulate an exoskeleton using their brains have regained some sensation and voluntary muscle control at sites below the spinal cord lesions that caused their paralysis, according to an international team of researchers. The scientists—among them the researchers who enabled a paralyzed man to execute the opening kick of the 2014 World Cup—reported the results of an eight-person trial in Scientific Reports today (August 11).

“Nobody ever imagined that one day we would be talking about the possibility of using brain-machine interfaces to induce partial neurological recovery in patients who have been diagnosed as having complete spinal cord injury,” study coauthor Miguel Nicolelis of the Duke University Medical Center told reporters during a conference call.

Nicolelis and colleagues had been studying the potential of a BMI-driven exoskeleton to give eight paralyzed people the ability to walk. But as the researchers trained the patients to manipulate either avatars in a virtual reality context or the exoskeleton for around an hour per day, twice a week, they noticed that some voluntary muscle movements and sensation returned to areas below the sites of the participants’ spinal cord lesions. “Our goal was simply to ...

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  • From 2017 to 2022, Bob Grant was Editor in Chief of The Scientist, where he started in 2007 as a Staff Writer. Before joining the team, he worked as a reporter at Audubon and earned a master’s degree in science journalism from New York University. In his previous life, he pursued a career in science, getting a bachelor’s degree in wildlife biology from Montana State University and a master’s degree in marine biology from the College of Charleston in South Carolina. Bob edited Reading Frames and other sections of the magazine.

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