Casting a Small Net

Scientists inject flexible, electronic mesh structures into mouse brains to track neurons in real time.

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LIEBER RESEARCH GROUP, HARVARD UNIVERSITY

Monitoring brain activity with single-neuron resolution in living animals just became more streamlined. In a report published in Nature Nanotechnology this week (June 8), researchers at Harvard University and China’s National Center for Nanoscience and Technology in Beijing demonstrated that they could inject a flexible metal-polymer electronic mesh into the brains of live mice and use it to monitor neuronal activity.

The study builds upon work done with the electronic mesh in cell culture models. “We were able to demonstrate that we could make this scaffold and culture cells within it, but we didn’t really have an idea how to insert that into pre-existing tissue,” study coauthor Charles Lieber, a chemist and nanoengineer at Harvard said in a statement.

By tightly rolling up the electronic ...

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