Citing Safety, French Institutions Temporarily Halt Prion Research

The three-month moratorium comes after a former prion researcher was diagnosed with Creutzfeldt-Jakob disease.

Written byAnnie Melchor
| 3 min read
micrograph showing red aggregating protein in mouse neurons

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ABOVE: Prion protein (shown in red) aggregating inside mouse neurons.
FLICKR, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, NIH

On Tuesday (July 27), five public research institutions in France announced they will suspend research on prions for three months. According to their joint press release, the decision was spurred by a case of Creutzfeldt-Jakob disease (CJD) in someone who may have been exposed to prions in a research lab.

According to Science, CJD is the most common prion disease in humans. Prions are infectious misfolded proteins that cause other proteins to misfold and aggregate in the brain. The US Centers for Disease Control and Prevention defines two types of CJD: classical, which generally arises through spontaneous protein misfolding in the brain, and variant CJD (vCJD), which is believed to be caused by exposure to the same prion that causes mad cow disease. There are no vaccines or treatments for CJD, which ...

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    Stephanie "Annie" Melchor got her PhD from the University of Virginia in 2020, studying how the immune response to the parasite Toxoplasma gondii leads to muscle wasting and tissue scarring in mice. While she is still an ardent immunology fangirl, she left the bench to become a science writer and received her master’s degree in science communication from the University of California, Santa Cruz, in 2021. You can check out more of her work here.

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