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Detecting Protein Clumps
Ruth Williams | Feb 1, 2018
A synthetic genetic tool called yTRAP allows high-throughput detection of protein aggregates in cells.
Prions Found in Skin of Creutzfeldt-Jakob Patients
Jef Akst | Nov 24, 2017
Infectious protein aggregates from the skin of human patients can cause disease in mice.
Bacterial Protein Acts as Prion in Yeast and
Jef Akst | Jan 17, 2017
produces a transcription factor that can aggregate and self-propagate a prion-like form, leading to genome-wide changes in gene expression in
, according to a study.
Blood Tests for Prion Disease
Joshua A. Krisch | Dec 22, 2016
Two studies describe methods for detecting these misfolded proteins in human blood samples.
Protein Folding Pioneer Dies
Kerry Grens | Oct 28, 2016
Susan Lindquist of MIT and the Whitehead Institute broke scientific ground on prions and heat shock proteins.
Week in Review: September 5–9
Jef Akst | Sep 9, 2016
Environmental magnetite in the human brain; prion structure takes shape; watching
evolve in real time; learning from others’ behavior
First Glimpse at Infectious Prion Shape
Abby Olena | Sep 8, 2016
The preliminary structure of the misfolded protein that causes mad cow disease and Creutzfeldt-Jakob disease looks like a coiled mattress spring.
Prions in Plants?
Tanya Lewis | Apr 26, 2016
A plant protein that behaves like a prion when inserted into yeast could enable a form of botanical memory, a study suggests.
Fearless about Folding
Anna Azvolinsky | Jan 1, 2016
Susan Lindquist has never shied away from letting her curiosity guide her research career.
Esteemed Virologist Dies
Karen Zusi | Dec 7, 2015
Richard Johnson, a pioneer in research on central nervous system infections, died last month at age 84.