Combinatorial Chemistry

MIX AND MATCH: Many useful compounds can be derived from combinatorial libraries, says Affymax's Mark Gallop. M.A. Gallop, R.W. Barrett, W.J. Dower, S.P.A. Fodor, E.M. Gordon, "Applications of combinatorial technologies to drug discovery. 1. Background and peptide combinatorial libraries" Journal of Medicinal Chemistry, 37: 1233-51, 1994 (Cited in more than 130 publications as of June 1996) E.M. Gordon, R.W. Barrett, W.J. Dower, S.P.A. Fodor, M.A. Gallop, "Applications of combinatorial techn

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MIX AND MATCH: Many useful compounds can be derived from combinatorial libraries, says Affymax's Mark Gallop.

M.A. Gallop, R.W. Barrett, W.J. Dower, S.P.A. Fodor, E.M. Gordon, "Applications of combinatorial technologies to drug discovery. 1. Background and peptide combinatorial libraries" Journal of Medicinal Chemistry, 37: 1233-51, 1994 (Cited in more than 130 publications as of June 1996)

E.M. Gordon, R.W. Barrett, W.J. Dower, S.P.A. Fodor, M.A. Gallop, "Applications of combinatorial technologies to drug discovery. 2. Combinatorial organic synthesis, library screening strategies, and future directions," Journal of Medicinal Chemistry, 37:1385-401, 1994. (Cited in more than 120 publications as of June 1996)

Comments by Mark A. Gallop, Affymax Research Institute, Palo Alto, Calif.

This pair of articles constitutes one of the first comprehensive looks at combinatorial chemistry, a field that has taken the scientific community by storm in the last several years (K.S. Brown, The Scientist, May 13, 1996, page 1). "The two ...

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