Deciphering How the Sexes Think

Editor's Note: This is the second article in a series on sex-based differences in the biology of males and females. Future articles in the series will cover sex-based differences in genetics, autoimmunity, and drug metabolism. Stereotypes aside, women and men do process information in singular ways. In the past, tests that tried to pinpoint those variations were fraught with inconsistencies and irregularities. But now, by studying the brain itself, researchers are learning that the sexes use dif

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A growing number of imaging studies reveal that women and men do not process certain cognitive information in the same way. For instance, researchers have found that women, when trying to exit a virtual 3-D maze, activated the right parietal cortex and right prefrontal cortex; men triggered the left hippocampus alone.1 When viewing emotionally disturbing images, women showed an increase in activity on the amygdala's left side; in men, it was the right side.2 The amygdala is a small brain region associated with mood and feelings.

Fertile research ground exists for researchers who want to figure out why and how this processing differs, and more specifically, how hormones are involved. And even bigger questions lie ahead in terms of assigning any adaptive significance to these differences. "I think that it's appropriate that we should expect a fair number of proximate processing differences because the ecology of being male and the ...

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