Denisovan DNA Reveals Human Roots

The ancient genomes of 50,000-year-old Denisovan teeth suggest the extinct species lived alongside Neanderthals and modern humans.

Written byBob Grant
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The Denisova cave in Siberia, where researchers recovered and sequenced the Denisovan remainsWIKIMEDIA, ????????????? Researchers have learned more about an extinct member of the human family tree by sequencing mitochondrial and nuclear DNA from 50,000-year-old molars found in a Siberian cave. The teeth belonged to Denisovans, an extinct hominin species that was first discovered in the cave in 2008, and the genome sequences suggest that the species lived alongside Homo sapiens as well as Neanderthals. The findings were published this week (November 16) in PNAS by a team led by the Max Planck Institute for Evolutionary Anthropology’s Svante Pääbo.

This ancient hominin milieu “was a lot like Middle-earth,” New York University molecular anthropologist Todd Disotell, who wasn’t involved with the study, told The New York Times. “There you’ve got elves and dwarves and hobbits and orcs,” while on the ancient Earth, “we had a ton of hominins that are closely related to us.”

Pääbo, who also led the first sequencing of Denisovan DNA from the cave in 2010, expressed similar fascination with the emerging picture of early hominin interaction in the area. “It’s an amazing place,” he told National Geographic, “because it’s actually the only place in the world where we know that three different groups of humans with very different histories all lived.”

The findings add to what little is known about Denisovans, ...

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  • From 2017 to 2022, Bob Grant was Editor in Chief of The Scientist, where he started in 2007 as a Staff Writer. Before joining the team, he worked as a reporter at Audubon and earned a master’s degree in science journalism from New York University. In his previous life, he pursued a career in science, getting a bachelor’s degree in wildlife biology from Montana State University and a master’s degree in marine biology from the College of Charleston in South Carolina. Bob edited Reading Frames and other sections of the magazine.

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