Skip to main content

Denisovan DNA Reveals Human Roots

The ancient genomes of 50,000-year-old Denisovan teeth suggest the extinct species lived alongside Neanderthals and modern humans.

Written byBob Grant
| 2 min read

Register for free to listen to this article
Listen with Speechify
0:00
2:00

The Denisova cave in Siberia, where researchers recovered and sequenced the Denisovan remainsWIKIMEDIA, ????????????? Researchers have learned more about an extinct member of the human family tree by sequencing mitochondrial and nuclear DNA from 50,000-year-old molars found in a Siberian cave. The teeth belonged to Denisovans, an extinct hominin species that was first discovered in the cave in 2008, and the genome sequences suggest that the species lived alongside Homo sapiens as well as Neanderthals. The findings were published this week (November 16) in PNAS by a team led by the Max Planck Institute for Evolutionary Anthropology’s Svante Pääbo.

This ancient hominin milieu “was a lot like Middle-earth,” New York University molecular anthropologist Todd Disotell, who wasn’t involved with the study, told The New York Times. “There you’ve got elves and dwarves and hobbits and orcs,” while on the ancient Earth, “we had a ton of hominins that are closely related to us.”

Pääbo, who also led the first sequencing of Denisovan DNA from the cave in 2010, expressed similar fascination with the emerging picture of early hominin interaction in the area. “It’s an amazing place,” he told National Geographic, “because it’s actually the only place in the world where we know that three different groups of humans with very different histories all lived.”

The findings add to what little is known about Denisovans, ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member?
Add The Scientist as a preferred source on Google

Add The Scientist as a preferred Google source to see more of our trusted coverage.

Meet the Author

  • From 2017 to 2022, Bob Grant was Editor in Chief of The Scientist, where he started in 2007 as a Staff Writer. Before joining the team, he worked as a reporter at Audubon and earned a master’s degree in science journalism from New York University. In his previous life, he pursued a career in science, getting a bachelor’s degree in wildlife biology from Montana State University and a master’s degree in marine biology from the College of Charleston in South Carolina. Bob edited Reading Frames and other sections of the magazine.

    View Full Profile

Related Topics

Related articles background image
August 2026 Digest cover
August 2026

Epic Fail: Sea-Monkeys Sabotage Fieldwork

When Barry Hicks set out to photograph thrombolites, thousands of unexpected visitors photobombed his underwater images.

View this Issue
Overcoming Immunotherapy Resistance in Liver Cancer

Overcoming Immunotherapy Resistance in Liver Cancer

Axion Biosystems
Optimizing NGS Library Preparation for Reliable Sequencing Data

Optimizing NGS Library Preparation for Reliable Sequencing Data

Covaris
Using TCR Repertoire Sequencing to Advance Immunology Research

Using TCR Repertoire Sequencing to Advance Immunology Research

Miltenyi
Mapping Clonal Mosaicism in Aging Tissues

Mapping Clonal Mosaicism in Aging Tissues

Mission bio

Products

Sino Biological Logo

Sino Biological Launches SuperNuclease ® Pro with Free Trial Program

Sino Biological Logo

Sino Biological Launches Precisely Characterized Full-Length p-Tau217 Protein to Advance Next-Generation Alzheimer’s Biomarker Assay Development

A photo of a scientist placing the Resipher device on a 96-well plate.

Resipher: Continuous Live-Cell Mitochondrial Respiration Monitoring in 96-Well Plates

Lucid Scientific logo
Conceptual image of ice and frost.

The VAULT100 PRO: Inside the most advanced Stirling Ultracold ULT freezer ever built.

Stirling Ultracold logo