Fish Oil May Slow Schizophrenia

Omega-3 supplementation reduced progression rates among people with early-stage symptoms of schizophrenia, according to a small trial.

Written byJef Akst
| 1 min read

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WIKIMEDIA, ODDMAN47Seven years ago, investigators enrolled 81 people aged 13 to 25 with early signs of schizophrenia in a clinical trial to test the effects of omega-3 fish oil pills. A paper published this week (August 11) in Nature Communications reported on 71 of those participants, pointing to a notable benefit of the supplements: only 10 percent of those taking fish oils ultimately developed schizophrenia, compared with 40 percent of the placebo group.

“I don’t want to sound like a cynic or a skeptic, but it’s almost too good to be true,” psychiatrist Jeffrey Lieberman of Columbia University Medical Center in New York City who was not involved in the study told ScienceNews.

Schizophrenia usually starts to manifest in the first 20 to 30 years of life, with minor delusions and paranoid thoughts often occurring in the teenage years or younger. But only about a third of people who present with such early symptoms eventually develop psychosis, New Scientist reported. After researchers found that the blood cells of schizophrenia patients have lower levels of omega-3 fatty acids than those of healthy controls, scientists in the field began to investigate the possibility that supplementing these compounds could treat the ...

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  • Jef (an unusual nickname for Jennifer) got her master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses. After four years of diving off the Gulf Coast of Tampa and performing behavioral experiments at the Tennessee Aquarium in Chattanooga, she left research to pursue a career in science writing. As The Scientist's managing editor, Jef edited features and oversaw the production of the TS Digest and quarterly print magazine. In 2022, her feature on uterus transplantation earned first place in the trade category of the Awards for Excellence in Health Care Journalism. She is a member of the National Association of Science Writers.

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