Skip to main content

Hagfish Slime Cells Tailored to Deter Predation

The Scientist spoke with Chapman University’s Yu Zeng about his lab’s finding that the slime-producing cells of the slippery marine fish vary with the creature’s size, which may be an adaptation to thwart different predators.

Written byChloe Tenn
| 5 min read
Hagfish slime on hands

Register for free to listen to this article
Listen with Speechify
0:00
5:00

ABOVE: Hagfish slime © ISTOCK.COM, FFENNEMA

Hagfish are notorious for their defensive slime, which can swell from a small secretion to a carload of goo in a fraction of a second. The slime is made up of a winding web of fibrous protein threads that trap the surrounding seawater, thus transforming it into a malicious mucus that suffocates the gills and jaws of attacking predators.

The biology of this slime has long fascinated materials scientists and evolutionary biologists alike, including Yu Zeng, an evolutionary biologist at Chapman University in California. Zeng and his colleagues decided to focus on the gland cells that produce the fish’s slick substance, and in their September 20 paper in Current Biology, they find that these slime cells differ in size and produce differently sized threads depending on the size of the hagfish, with larger hagfish possessing much larger thread-producing cells than would be expected based ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member?
Add The Scientist as a preferred source on Google

Add The Scientist as a preferred Google source to see more of our trusted coverage.

Meet the Author

  • young woman smiling

    Chloe Tenn is a graduate of North Carolina State University, where she studied neurobiology, English, and forensic science. Fascinated by the intersection of science and society, she has written for organizations such as NC Sea Grant and the Smithsonian. Chloe also works as a freelancer with AZoNetwork, where she ghostwrites content for biotechnology, pharmaceutical, food, energy, and environmental companies. She recently completed her MSc Science Communication from the University of Manchester, where she researched how online communication impacts disease stigma. You can check out more of her work here.

    View Full Profile

Related Topics

The Scientist Digest cover September 2026
September 2026

Multiplex Microscopy Becomes Easier with Encoded Antibodies

A new system that enables researchers to uniquely tag monoclonal antibodies for use in microscopy could help simplify complex imaging studies.

View this Issue
Essential Genes Are Dominantly Activated by Single Transcription Factors

Essential Genes Are Dominantly Activated by Single Transcription Factors

EpiCypher Logo
Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Alamar Biosciences logo
Engineering CAR-Neutrophils In Vivo to Target Glioblastoma

Engineering CAR-Neutrophils In Vivo to Target Glioblastoma

Miltenyi
Best Practices for qPCR Assay Design and Optimization

Best Practices for qPCR Assay Design and Optimization

Bio-Rad

Products

Closeup image of a multi channel pipette dispensing pink liquid into a 96-well plate.

The ASSIST PLUS pipetting robot for affordable workflow automation

Integra Logo
Single cells in suspension

Rapidly isolate primary cells and make uniform single-cell suspensions with Corning® Cell Strainers

Corning logo
Abstract image representing cell membranes linked together.

CellBrite® Steady Membrane Stain: Cell surface staining built for real-time imaging

Biotium
sino biological logo

Monod Bio Licenses AI-designed Protein Technologies to SignalChem Biotech for Custom Discovery Assays