How to Build a Better Flu Shot

In the midst of a brutal influenza season, researchers are working toward a single vaccine that could ward off multiple strains of the virus.

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ISTOCK, SAEMILEEThe flu is dominating the U.S. It is now widespread in 49 states and Puerto Rico and has sickened thousands since October, the Centers for Disease Control and Prevention reports. Tens of thousands die each year as a result of the flu.

“We need to make the universal flu vaccine a higher priority than it has been,” Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases (NIAID), tells The Scientist.

Researchers have long sought a flu vaccine that would protect individuals season after season with just a single inoculation, similar to the measles or chickenpox vaccines. But unlike the measles or chickenpox virus, which are both fairly stable in genetic structure, the influenza virus has many rapidly mutating strains. And because the strains mutate so quickly, making them unrecognizable to the body’s immune system, a new flu vaccine has to be developed each year or every other year.

Micrograph of H1N1 virusCDC INFLUENZA LABORATORY

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Meet the Author

  • Ashley Yeager

    Ashley started at The Scientist in 2018. Before joining the staff, she worked as a freelance editor and writer, a writer at the Simons Foundation, and a web producer at Science News, among other positions. She holds a bachelor’s degree in journalism from the University of Tennessee, Knoxville, and a master’s degree in science writing from MIT. Ashley edits the Scientist to Watch and Profile sections of the magazine and writes news, features, and other stories for both online and print.

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