Impossible Vaccine Tames Staphylococcus aureus

Image: Courtesy of Ali Fattom THE END IS NEAR: S. aureus attached to tissue If Scottish surgeon Alexander Ogsten ever daydreamed that discovering Staphylococcus aureus would win acclamation, it was before he crossed paths with the British Medical Journal and came away the worse for it, squashed like a cockroach caught scurrying across a tray of tea and crumpets. Upbraiding the upstart for daring to step beyond his place, the editor dismissed Ogsten's 1881 paper on the bacterium, jotting

Written byTom Hollon
| 8 min read

Register for free to listen to this article
Listen with Speechify
0:00
8:00
Share

If Scottish surgeon Alexander Ogsten ever daydreamed that discovering Staphylococcus aureus would win acclamation, it was before he crossed paths with the British Medical Journal and came away the worse for it, squashed like a cockroach caught scurrying across a tray of tea and crumpets. Upbraiding the upstart for daring to step beyond his place, the editor dismissed Ogsten's 1881 paper on the bacterium, jotting in swift strokes of ink that "little of any worth comes from Scotland."

Let us pause a moment to savor this naked insult, those of us who admit to guilty pleasure in watching scientists fight, for here the curtains opened upon a field in which interesting acrimony has often flourished right alongside interesting science. Credit this state of delight to the molecular properties of S. aureus, being as it is somewhat different from those of its brethren, and so a continual source of disagreement and ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Meet the Author

Published In

Share
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies